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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 79 for “"patient prognosis"”.

  1. Local Estimation of Patient Prognosis

    Kosel, Alison2016

    Statistical methods that can provide patients and their healthcare providers with individual predictions are needed so that informed medical decisions can be made. Ideally an individual prediction would display the full range of possible outcomes (full predictive distribution), would be obtained …

    washington Repository record

  2. Characterization of aspects of leukemia biology and association with patient prognosis

    Seyfried, FelixUniversität Ulm

    ulm-diss Repository record

  3. MRI Radiomics Modeling and Survival Prediction of Pancreatic Ductal Adenocarcinoma Patients

    Marasco, JacobCreighton University2023

    … clinical and image-based, may be used to improve patient prognosis after diagnosis of this disease.Quantitative imaging analysis, namely radiomics, has been gaining popularity in medicine over recent years in identifying cancer variants that are particularly difficult to diagnose when symptoms are …

    creighton Repository record

  4. Treatment Response Prediction in Acute Myeloid Leukemia Patients

    Lambion, Danielle2022

    Predicting acute myeloid leukemia (AML) patient treatment response has the potential to impact clinical decisions. A prediction given at the time of diagnosis for treatment response can assist physicians in making effective treatment decisions and improving patient prognosis. This project aimed to …

    washington Repository record

  5. Role of Lymphocyte Populations Following Allogeneic Haematopoietic Stem Cell Transplantation // Роля на лимфоцитните популации след алогенна трансплантация на хемопоетични стволови клетки

    Petrov, Yavor, Петров, ЯворMedical University of Varna2025

    … process, which has critical importance for patient prognosis. Lymphocyte subpopulations play a key role in the immune regulation of recipients, and an imbalance in their number and function can lead to severe consequences – GVHD, relapse of the underlying disease, infectious and …

    varna Repository record

  6. TO INVESTIGATE THE ROLE OF RNF8 IN REGULATING MITOTIC PROGRESSION IN GLIOMAS

    CHUAH YOU HENG2024

    … Indeed, low RNF8 expression portends poor patient prognosis in glioma patients. Importantly, our mechanistic findings led to the rational combination of PLK1 and HSP90 inhibitors that elicit an additive effect in reducing GSC proliferation and stemness. Thus, our study has unveiled a novel …

    nus Repository record

  7. Decoding the RNA cargo of plasma-derived extracellular vesicles in metastatic castration-resistant prostate cancer

    Vannuccini, FedericoUniversità degli studi di Trento2025

    … castration-resistant prostate cancer (mCRPC) patients, treated with Enzalutamide in a chemo-naïve setting. Specifically, it incorporates EV physical characterization, EV-RNA and matched cfDNA genomics. The use of total RNA sequencing (RNA-seq) enabled the detection of both coding and …

    trento Repository record

  8. The international prognostic score and HIV status predict red cell concentrate transfusion needs in Hodgkin lymphoma

    Simba, KudakwasheDepartment of Medicine2025

    … burden of anaemia among Hodgkin Lymphoma (HL) patients, data evaluating red cell concentrate transfusion is limited. We retrospectively studied 285 newly diagnosed HL patients who received first-line ABVD treatment at Groote Schuur Hospital, Cape Town. HIV prevalence in the cohort was 39.5% and …

    cape-town Repository record

  9. Delineating metastasis in MSS colorectal cancer by single - cell RNA sequencing

    You, Shuangjie, <p>0009-0009-7825-3861</p>2025

    … insights into drug development to improve patient prognosis.</p>

    uthsc Repository record

  10. Correlation between phenotypes or genotypes of Clostridium difficile and clinical outcome from Clostridium difficile infections at Health Sciences North

    Lefebvre, Sebastien RogerLaurentian University of Sudbury2016

    … in health-care facilities. Its effect on patients can be detrimental to their recovery, sometimes leading to death; the catalyst to Clostridium difficile infection (CDI) is treatment by antibiotics. Focusing research on some of C. difficile’s genotypes and phenotypes, we hoped to be able …

    laurentian Repository record

  11. The relationship between BRAF genetic alterations and the risk of tumour recurrence in Pilocytic Astrocytomas in children diagnosed at Red Cross Children's Hospital over a 33-year period

    Viljoen, NandiDepartment of Clinical Laboratory Sciences2024

    … reports on the impact of specific mutations on patient prognosis are controversial. 5–8 Advances in molecular techniques have opened the door for further studies to determine the relationship between these BRAF alterations (point mutations and gene fusions) and the risk of tumour recurrence. …

    cape-town Repository record

  12. Förster Resonance Energy Transfer-Based Quantification of D-2-Hydroxyglutarate & Locked Nucleic Acid Loop-Mediated Isothermal Amplification Mediated Detection of IDH1-R132 Single Nucleotide Variants in Glioma

    Choate, Kristian A2029

    … gliomas which provides valuable information on patient prognosis and treatment. Targeted therapies including maximal surgical resection and pharmaceutical mutant IDH inhibitors offer life extending benefits; however, currently implemented assays for the detection of <em>IDH1</em> mutations do …

    nmu Repository record

  13. Predicting mortality for patients in critical care : a univariate flagging approach

    Sheth, MalloryMassachusetts Institute of Technology2015

    Predicting outcomes for critically ill patients is a topic of considerable interest. The most widely used models utilize data from early in a patient's stay to predict risk of death. While research has shown that use of daily information, including trends in key variables, can improve predictions …

    mit Repository record

  14. Endosomal Trafficking and Exosomal Secretion of Egfrviii

    Memarzadeh, Kimiya, <p>https://orcid.org/0000-0003-1737-663X</p>2020

    … (GBM) tumors and is associated with poor patient prognosis. Persistent signaling due to a lack of the EGFR ectodomain and inefficient degradation have been suggested to underlie the tumorgenic properties of EGFRvIII. I observed that, like the parental EGFR, EGFRvIII is internalized into …

    uthsc Repository record

  15. Novel Regulation of the Cell Cycle During Cell Fate Decisions in the Central Nervous System

    Lubanska, Dorota D.University of Windsor2013

    … of the SPDYA gene loci correlates with poor patient prognosis. We show that Spy1 is expressed at high levels in neurogenic regions of the adult brain and the overexpression of Spy1 significantly increases cell proliferation parameters including the number and longevity of neurospheres. These …

    windsor Repository record

  16. Characterisation of the Helix pomatia agglutinin binding glycoproteins of colorectal cancer cell lines and tissue samples

    Saint-Guirons, J.University of Westminster2007

    … both as targets and as a means of predicting patient prognosis. The lectin from the Roman snail Helix pomatia (HPA) has attracted interest as tool for the detection of metastatic colorectal cancer but the HPA binding partners have remained poorly characterised. We established an in vitro model …

    westminster Repository record

  17. INVESTIGATING THE ROLE OF LIPID DROPLETS AS INTRACELLULAR MECHANICAL STRESSORS IN NON-ALCOHOLIC FATTY LIVER DISEASE

    Loneker, Abigail, Erin2023

    … is correlated with cancer development and patient prognosis, and is used clinically in disease surveillance. However, patients with non-alcoholic fatty liver disease (NAFLD) and lipid-droplet-filled hepatocytes can develop cancer in non-cirrhotic, relatively soft tissue. Given the clear …

    penn Repository record

  18. Sex Differences in Collateral Remodeling Following Hindlimb Arterial Occlusion

    Burckhardt, Laura2017

    … limb ischemia in women, as well as worse prognosis and decreased survival post myocardial infarction. Therefore, understanding the possible differences in underlying vascular compensation mechanisms is crucial. With arterial occlusions, necrosis and tissue injury can be naturally mitigated …

    calpoly Repository record

  19. A study of the robustness of Cox's proportional hazards model used in testing for covariate effects

    Fei, MingweiKansas State University2012

    … quantities or covariates, potentially affect patient prognosis, it is often desirable to investigate one factor effect adjust for the impact of others. This report offered a solution to choose appropriate model in testing covariate effects under different situations. In real life, we are very …

    ksu Repository record

  20. The development and evaluation of multifunctional silver iron-oxide hybrid nanoparticles towards enhanced pancreatic cancer therapy

    Evans, Lauren L.University of Strathclyde2024

    … Lack of drug efficacy is a major issue faced by patients. The nanomedicine community are striving to develop innovative technologies, such as nanoparticle drug delivery systems, to address this issue. Multifunctional silver iron-oxide hybrid nanoparticles (AgHNPs) are presented as a …

    strathclyde Repository record

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