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Showing 1 to 2 of 2 for “"pathway refactoring"”.
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Development and application of synthetic biology tools for natural product research
… of tremendously large numbers of biosynthetic pathways for natural products directly from genomic database, which indicates Nature’s great potential of making these molecules remains to be explored. However, most of these uncharacterized pathways are naturally under negative regulation or …
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Pathway engineering for the discovery and optimized production of phosphonic acids
… feasible manner. In this work we implement pathway engineering strategies to further lower these barriers, with a focus on the class of natural products called phosphonic acids. These compounds have a stable carbon-phosphorus bond, which allow them to mimic phosphate esters and carboxylic …