Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"pathway modeling"”.
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Automated Care Pathway Modeling Using Agentic and Knowledge-Aware LLMs
Clinical pathways (CPWs) translate evidence-based guidance into stepwise care but are often disseminated as free text, obscuring control-flow semantics needed for clarity and computability. Formalizing CPWs as process models - e.g., in the Business Process Model and Notation (BPMN) - improves …
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New Algorithms for Mining Network Datasets: Applications to Phenotype and Pathway Modeling
… experiments, and methods to probe metabolic pathways. Efficient and comprehensive computational approaches are required to model these screens and gain insight into the nature of biological networks. This thesis presents three new algorithms to model and mine network datasets. First, we …
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Spatiotemporal modeling and model restructuration approaches in studies of intracellular signalling pathways
… the complex phenomena of cell transduction pathways and cell biology in a single cell. Mathematical modeling and experimental evaluation are widely used approaches for this kind of research. Firstly, A multiscale framework for protein-protein interaction has been established using Brownian …
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Metabolic network design and engineering in Escherichia coli
… cellular properties. The succinate synthesis pathways in E. coli were chosen as the model system for network design and optimization. The ultimate goal is to create succinate production systems in E. coli that not only achieve the maximum theoretical yield of succinate, but also are highly …
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Pathways to Net Zero: Financing Strategies For Low-Income Homeowners
… To address this problem, we present a retrofit pathway modeling framework to accurately predict the time required to achieve comprehensive retrofits for the homeowner. Taking retrofit cost and annual energy saving into account, we are proposing a new Government sponsored and led financing …
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Bridging the Gap between Deterministic and Stochastic Modeling with Automatic Scaling and Conversion
… are introduced and implemented in the JigCell modeling environment. Our tool makes it easier for the modeler to include complete details as well as to convert the model. Stochastic simulations are known for being computationally intensive, and thus require high performance computing facilities …
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Probabilistic Approximation and Analysis Techniques for Bio-Pathway Models
Quantitative modeling of bio-pathway dynamics is crucial to the system-level understanding of cellular functions and behavior. Currently, a common method of representing bio-pathways is through a system of ordinary differential equations (ODEs). However, calibrating and analyzing large ODE-based …