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Showing 1 to 3 of 3 for “"pathological neovascularization"”.
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ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?
… of the molecule N-CAM is protecting against the pathological neovascularization affecting diabetic patients. The last 10 years have proven it possible to cure diabetes through transplantations of islets of Langerhans from cadaveric donors. The transplantations requires suppression of the immune …
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Evaluation Of HIF Inhibitors For The Treatment of Ocular Neovascular Diseases
… genes under hypoxia is the fundamental cause of pathological neovascularization in ocular diseases and cancers. Thus, the inhibitors of the HIF pathway or key regulators such as histone demethylases (KDMs), that amplify HIF signaling, can have profound therapeutic value for these diseases. This …
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The traditionally protective cystathionine gamma-lyase/hydrogen sulfide pathway contributes to pathological retinal neovascularization in oxygen-induced retinopathy
… tissue. However, retinal ischemia can cause pathological vessel growth which disrupts the precise ocular architecture and leads to irreversible vision loss. Our goal was to determine the role of the CSE/H2S pathway in ischemia-induced pathological retinal neovascularization (NV). C57BL/6 CSE …