Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"pathogenic E. coli"”.
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Characterization of Clinical and Commensal Escherichia coli Isolates from an Integrated Turkey Operation
Pathogenic E. coli infections cause approximately one quarter of disease losses in commercial turkey flocks. A small subgroup of E. coli causes most infections. Epidemiologic studies of this disease have been hindered by a lack of reliable markers to discriminate between pathogenic and fecal E. …
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Investigating behaviors of zoonotic and human pathogens on plants
… It is hypothesized that environmental E. coli not typically associated with the ability to cause disease in humans could potentially be responsible for some of these cases. The role of avian pathogenic E. coli (APEC) in human disease remains questionable, although genomic evaluations of …
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Comparing the distribution of pathogenic bacteria and common indicator microorganisms in biofilms on different surface types in an agricultural watershed in British Columbia (Canada)
… focused on whether biofilms can act as sinks for pathogenic organisms and could be monitored to protect public health. To do so, we monitored the presence of faecal contamination indicators (heterotrophic plate counts, faecal coliforms, enterococci, and E. coli) and particular pathogens (E. coli …
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Studies on the Role of Histone-like Proteins in Gene Regulation in Uropathogenic Escherichia coli Isolate 536
… histone-like proteins in gene regulation in uropathogenic Escherichia coli isolate 536 was monitored. The histone-like nucleoid structuring protein H-NS is a global regulator in Escherichia coli that has been intensively studied in non-pathogenic strains. No comprehensive study on the role of …
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Phenotypic, Genotypic, and Pathogenic Evaluation of E. coli ST131 Clinical Isolates
Since their identification in 2008, E. coli ST131 isolates have become a major cause of cystitis and pyelonephritis. However, these strains are not known to encode different, or increased numbers of virulence factors compared to other sequence types of pathogenic E. coli. To date, no data in the …
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Characterization of a salmonella phage using omic tools and mathematical models to predict host-phage interaction
The increasing resistance of pathogenic bacteria to antibiotics in recent years has become a major problem in controlling infections in animals and humans. Salmonella enterica, which causes human food poisoning worldwide, is one of the most problematic bacteria with significant incidence in …
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Characterization of E. coli strains from rural communities in the Vhembe District (Limpopo South Africa)
Background: Escherichia coli is a facultative anaerobic bacterium that forms part of the gut microbiota. It is used as an indicator that confirms recent faecal contamination. E. coli have been identified amongst the pathogens that are mostly responsible for moderate to severe diarrheal outbreaks in …
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A Larval Zebrafish (Danio Rerio) Model of Adherent-Invasive Escherichia Coli Infections
… (IBD), including Crohn’s disease and ulcerative colitis, is a broad term for chronic intestinal disorders that severely impact patient morbidity and quality of life. The global prevalence of IBD is rising, with over one million patients affected in the US alone. Adherent-invasive <em>E. coli …
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Assembly of the O Antigen in the Highly Pathogenic Escherichia Coli Serotype O104:H4
Escherichia coli serotype O104:H4 (ECO104) is an intestinal pathogen that causes severe bloody diarrhea and hemolytic-uremic syndrome, which can lead to kidney failure and death. Lipopolysaccharides (LPS) are important virulence factors in Gram-negative bacteria and our goal is to understand the …
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Comparative genotypic and phenotypic characteristics of human associated extraintestinal Escherichia coli isolated from cats and dogs
Escherichia coli extraintestinal infections (ExPEC) cause significant disease in humans and companion animals (cats and dogs) predominantly urinary tract infections, but also sepsis and neonatal meningitis. E. coli also causes avian pathogenic E. coli (APEC), a very important cause of mortality and …
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Comparative genotypic and phenotypic characteristics of human associated extraintestinal Escherichia coli isolated from cats and dogs
Escherichia coli extraintestinal infections (ExPEC) cause significant disease in humans and companion animals (cats and dogs) predominantly urinary tract infections, but also sepsis and neonatal meningitis. E. coli also causes avian pathogenic E. coli (APEC), a very important cause of mortality and …
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Evolution-Inspired Design of Bacterial Biosensors
… a subset of these AMPs in S. Typhimurium and E. coli using a variety of PhoPQ responsive promoters. We show that PhoPQ homologs from extraintestinal pathogenic E. coli and K. pneumoniae, which occupy in vivo niches, exhibit distinct activation profiles, providing new insights into the …
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Investigation of the intracellular trafficking pathways of the dermonecrotic toxin family
… 1, 2, and 3 (CNF1, 2 and 3) from Escherichia coli (E. coli), the cytotoxic necrotizing factor Y (CNFY) from Yersinia pseudotuberculosis (Y. pseudotuberculosis), and the dermonecrotic toxin (DNT) from Bordetella species are related by sequence similarity and share similar intracellular …
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Acid adaptation of Escherichia coli O157:H7 in fermented goat milk
… on the survival and growth of Escherichia coli in broth and fermented goat milk. In the first phase of the study, acid resistance of E. coli O157:H7 strain UT 10 and E. coli ATCC 25922 was determined in brain heart infusion broth at pH 7.4, 4.5 and 2.5. Variations due to acid stress in the …
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Development of a Biofilm Model for Evaluating Poultry Drinking Water Sanitation Procedures
… Experiment 4 also included seeding the avian pathogenic E. coli sero group O2 strain in pathogen free water containing 7 d old biofilm test coupons and determining if it would incorporate into the biofilm community post 48- hour exposure. Sanitizers tested on the coupons included chlorine …
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Populations of Escherichia coli in clinical samples of Urinary Tract Infections and bacteraemia
Extraintestinal pathogenic E. coli (ExPEC) strains are the main etiologic agent of urinary tract infections (UTIs). ExPEC strains are also reported to be the most common cause of bacteraemia in the world, which often originate from UTI. The population structure of UTI E. coli strains is well …
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Characterization of OmpT: An outer membrane vesicle protease Escherichia coli that attenuates blood coagulation.
Escherichia coli O157:H7 is an emerging food-borne and water-borne pathogen that belongs to Enterohemorrhaghic pathogenic group of bacteria. E. coli O157:H7 colonizes the gastrointestinal tract and is responsible for hemorrahagic colitis, renal failure, bloody diarrhoea, hemolytic uremic syndrome, …
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Nutritional parameters associated with enteric Escherichia coli and rotavirus in poults
… were conducted to investigate the effects of E. coli and rotavirus as causative agents in producing infectious stunting syndrome of poults. The syndrome, as it occurs commercially, was characterized in two experiments to produce decreased digestible dry matter and nitrogen as well as increased …
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Molecular basis of NAIP/NLRC4 inflammasome activation by flagellin
… using S. Typhimurium SL1344 and the non-pathogenic E. coli strain K12-MG1655. An important part of my work was to try and determine which regions of fliC are required for NAIP/NLRC4 inflammasome activation and whether they can be mutated while preserving motility. To do this a panel of …
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