Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"pathogen sensing"”.
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The Role of Galectin-3 in Pathogen Sensing and Cell Autonomous Defense
<p>There is a dynamic interplay between pathogens and their hosts. This interplay has resulted in a constant struggle where the host is attempting to clear the pathogen, while the pathogen attempts to subvert the host’s immune system. The result of the back and forth has resulted in what is called …
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The cell-intrinsic innate immune response to DNA damage in human cells
… required components of the cytoplasmic DNA sensing pathway, the predominantly nuclear sensor IFI16 and the cytoplasmic adaptor protein STING, but was independent of the enzyme cGAS, which is essential for the immune response to cytosolic DNA. The transcriptional and signalling profiles of …
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DISSECTING THE ROLES OF DISTINCT DENDRITIC CELL SUBSETS IN THE IMMUNE RESPONSE TO THE INTRACELLULAR BACTERIAL PATHOGEN, LISTERIA MONOCYTOGENES
… the development of protective immunity to many pathogens and link the innate and adaptive immune systems. While DC as a whole have been studied extensively and are widely known for their ability to prime naïve T cells, there is much yet to be discovered about DC biology and function in responses …
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Computational Methods for Investigating Dendritic Cell Biology
… the host from a large number of ever-evolving pathogens. In vertebrates, the immune response results from the interplay of two cellular systems: the innate immunity and the adaptive immunity. In the past decades, dendritic cells have emerged as major players in the modulation of the immune …
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A liposome-based ion release impedance sensor for HIV detection at the point-of-care
… have been reported toward the point-of-care sensing of biological entities, none has yet emerged as a comprehensive solution to the fundamental problems of diagnostic testing in resource-limited settings. In strides toward a platform for low-cost, rapid, easy-to-use point-of-care diagnostics, …
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Protein Engineering for Biomedical Materials
… as bio-recognition modules for biomedical sensing and imaging. Chapter three provides an overview of the most recent advances in engineering of repeat proteins in the aforementioned field. Chapter four discusses my contribution to this field. We have designed a de novo repeat protein …