Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"pathogen genomics"”.
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Host and pathogen genomics: the molecular repertoire of soybean and Sclerotinia interactions
… de Bary is an economically important soybean pathogen in the U.S. and worldwide. Understanding the disease caused by this fungus can help in controlling it. In the present study, genome-wide screenings were carried out to identify soybean mRNAs and small RNAs that change in expression during …
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From gut microbiome to pathogen genomics: Understanding antimicrobial resistance in Southeast Asia and Salmonella Paratyphi A
… public health risks it poses. Additionally, the genomics and AMR mechanisms of Salmonella Paratyphi A, a major cause of enteric fever in Asia were explored. The distribution and ecology of S. Paratyphi A are closely linked to the gut microbiome potentially contributing to resistance gene …
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Exploring the phylodynamics, genetic reassortment and RNA secondary structure formation patterns of orthomyxoviruses by comparative sequence analysis
… resistance. The studies herein demonstrate that pathogen genomics-based analytical approaches are useful both for understanding the mechanisms that drive the evolution and spread of rapidly evolving viral pathogens such as orthomyxoviruses, and for illuminating how these approaches could be …
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AN INTEGRATED APPROACH TO THE DEVELOPMENT OF RESISTANCE TO COMMON BACTERIAL BLIGHT IN COMMON BEAN (PHASEOLUS VULGARIS)
… yet resistance is quantitative and influenced by pathogen diversity. Most known quantitative trait loci (QTLs) derive from Mesoamerican germplasm, leaving Andean market classes such as cranberry bean understudied. This thesis uses a multi‐scale approach, combining QTL mapping, transcriptomics and …
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Scalable Tools for High-throughput Viral Sequence Analysis
… detection and subtyping framework for pathogen sequences. ANVIL's performance was benchmarked using two large HIV datasets collected from the Los Alamos HIV Sequence Database and the UK HIV Drug Resistance Database, as well as on simulated data. Finally, I present a computational …
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Host and pathogen genetics associated with pneumococcal meningitis
… The contribution of variation in host and pathogen genetics to pneumococcal meningitis is unknown. In this thesis I develop and apply statistical genetics techniques to identify genomic variation associated with the various stages of pneumococcal meningitis, including colonisation, invasion …