Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 43 for “"passive Diffusion"”.
-
A mathematical model of the airway epithelium: Computational studies of ion and water balance
… Membrane transport processes included apical passive diffusion of sodium and chloride, basolateral passive diffusion of potassium, basolateral sodium-potassium active transport, basolateral sodium-potassium-chloride cotransport, water permeation across all membranes, and nonselective …
-
Influence of environmental factors on molecular transport through bacterial membranes
… protein, Mtr permease, resulted in enhanced passive diffusion across the membrane. For the second project (Chapter 5), we examined the influence of temperature on the rate of passive diffusion across a membrane, both in model systems (liposomes) and in living cells (E. coli). For both …
-
A Comparison of Theoretical and Actual Coumarin Exudation Under Iron Limitation to Understand Root Exudation Mechanics
… mass-transport mechanisms, including active and passive transport types, though the latter is not well-studied despite being labelled a significant driver of low molecular weight metabolite exudation. This research investigates the generally accepted assumption that low molecular weight …
-
Mechanism of transmissible gastroenteritis virus nsp1-mediated translation inhibition
… cells. TGEV nsp1 can enter the nucleus via passive diffusion because its molecular weight (~9 kDa) is below the passive diffusion exclusion limit of the nuclear pore complex. Both TGEV infection and TGEV nsp1 protein expression inhibit cellular protein synthesis. TGEV nsp1 expression …
-
Molecular Size and Charge Effects on Nucleocytoplasmic Transport Studied By Single-Molecule Microscopy
… in the NPC allows for two transport modes: passive diffusion of small signal-independent molecules (< 20-40 kDa) and transport-receptor facilitated translocation of signal-dependant cargoes. The molecular size of a cargo molecule is one of the important parameters that determine the final …
-
Inhibition of Cysteine Protease by Platinum (II) Diamine Complexes
… the cell through copper transporter CTR1 by passive diffusion and bind to DNA and proteins. Cisplatin is found to inhibit several enzymes targeting cysteine, histidine and methionine residues, which are expected to be responsible for its anticancer activity. A better understanding of how the …
-
An InVitro Leakage and Viscosity Analysis of Root End Filling Materials
… of root end fillings was assessed in a passive diffusion model. Leakage groups were compared with a one-way ANOVA (p < 0.05). No significant difference was found. Particle size and shape were evaluated with the SEM. MTA Angelus Fluid has a lower viscosity than the other materials tested. …
-
The Surface Properties of the Mammalian Small Intestine: their role in the Absorption of Nutrients and their Variation in Health and Disease
… mechanism but supported a model of facilitated passive diffusion of folates after conversion to neutral forms in the surface acid microclimate. An elevation in the surface microclimate pH was found to cause a decrease in folate absorption. 5-meTHF does not undergo metabolic alteration during …
-
The contribution of construction materials to the airborne radon concentrations in an underground facility
… soil gas to the ambient air, were sampled with passive diffusion charcoal canisters. Results, measured by gamma spectroscopy, indicate the average exhalation rate for the native material surfaces was 0.0021 +/- 0.0002 Bq cm -2 hr-1; much higher than that for the fiber crete surface at 0.00099 …
-
FUNCTIONAL ADAPTATION OF THE RUMINAL EPITHELIUM
… are absorbed across the rumen epithelium via passive diffusion or protein-mediated transport, however, the rate and degree to which these pathways adapt to a change in diet fermentability is unknown. Furthermore, Na+ flux is partially determined by SCFA absorption, and thus is a key indicator …
-
Apical and radial pH diffusion through root dentin from five modern intracanal medicaments: a twelve-week evaluation of alkaline dynamics
… temporal and spatial behavior of hydroxyl ion diffusion through root dentin from five contemporary intracanal medicaments over 12 weeks, with emphasis on vehicle composition and apical diffusion beyond the medicament terminus. METHODS: Sixty-six extracted single-rooted human teeth were prepared …
-
Analysis of a model to describe lead transport by the small intestine
… intestinal tissue surface; and a concurrent slow passive diffusion of lead cations across the intestinal epithelium. The presence of methylxanthines, which diminish the size of the intercellular channels, were found to decrease the rate of lead cation transport, and indicated a paracellular route …
-
Expanding the Spiroligomers Toolbox as Protein-Protein Interaction Inhibitors
… enter human liver cancer cells through passive diffusion and induces a biological response in both a dose- and time-dependent manner. The synthesis of additional spiroligomer analogues achieved low micromolar to high nanomolar range activity during screening in direct and competitive …
-
Development of a microfluidic device for blood oxygenation by photocatalysis
… with a microfluidic network that facilitates diffusion of the dissolved oxygen to red blood cells. While true pulmonary respiration relies on passive diffusion of oxygen gas from the environment to the blood, the proposed device differs in that it generates oxygen directly from the water in …
-
Distribution and regulation of ion channels in neurons: Quantitative studies of global ion channel transport and homeostatic synaptic scaling
… including quantitative measurements of both passive diffusion and active microtubule-based transport in both axons and dendrites (Chapters 3 and 5). Mass action models reveal that measured transport profiles corroborate discrepancies in Kv4.2 localization both between neurite types and along …
-
The effect of protozoan grazers on the cycling of polychlorinated biphenyls (PCBs) in marine systems
… calculations predicted rapid equilibration via passive diffusion. Experimentally, no difference in equilibration time was noted between grazing and non-grazing protozoa, indicating that diffusion was the primary uptake pathway for these organisms. The results were extended to determine the …
-
To Investigate The Impact Of Gut Bacteria On Efflux Transporter Expression And Function In Gastrointestinal Mucosae
… cell layers occurs by active transport and passive diffusion. Using mouse models that differ in bacterial content and fluorescence scanning, and live imaging techniques we studied the impact of bacteria on protein expression and function. The accumulation of membrane permeable acetoxymethyl …
-
Selective Labelling of Peptides with Organometallic Compounds - Chemical and Biological Characterization
… showed higher permeation, as ex-pected for a passive diffusion mechanism.
-
Investigating Hybrid Cyclic/Linear and Linear Peptides as Vehicles for Nucleic Acid Delivery
… molecule, which cannot enter the cell through passive diffusion and/or interaction with the cell membrane. Cell-penetrating peptides (CPPs) offer a unique carrier for nucleic acid delivery, where positively charged components of CPP bind to the negatively charged nucleic acid and the …
-
The Role of Surface Properties in the Transport of Folates Across the Intestine
… acid and 5-methyltetrahydrofolic acid involves passive diffusion following conversion to the neutral species within the acid microclimate.
Page 1 of 3