Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"paraxial mesoderm"”.
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The evolution of somitogenesis: Mechanisms of paraxial mesoderm elongation in zebrafish and other vertebrates
… involves elongation and segmentation of the paraxial mesoderm to form somites. Although the segmentation aspect of this has been widely studied, the elongation aspect is not well understood. Posterior growth is widely assumed to be the main driver, but there is very little evidence for this – …
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The role of pax genes in vertebrate segmentation
… and Pax7 in particular are associated with the paraxial mesoderm, especially the development of the myogenic lineage. However, recent studies have suggested that Pax3 and Pax7 may have earlier, morphogenetic roles in the segementation of the paraxial mesoderm. Here we examine the expression of …
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CONTRIBUTIONS OF THE 3' HOX GENES, HOXA1, HOXB1, AND HOXB2, TO PATTERNING OF THE AXIAL SKELETON DURING DEVELOPMENT
… Hoxb2, play a critical role in patterning the paraxial mesoderm that will give rise to the axial skeleton.
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Investigation of cell movement and the associated cytoskeleton during chick gastrulation and somitogenesis
… gather at the centre of the embryo, bands of paraxial mesoderm that lie either side of the neural tube separate into somites. As new somites form caudally, the more rostral somites undergo a process of morphogenesis. Each somite divides into two regions: the dermomyotome and the sclerotome. …
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Role of Xenopus Pitx3 during early development.
… expression is restricted to lateral prechordal mesoderm, anterior paraxial mesoderm, a crescent of anterior sensorial ectoderm, and a discrete spot which is fated to form Rathke's pouch. xPitx3 is expressed throughout lens induction in the presumptive lens ectoderm, lens placode, and later in …
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Date with Destiny: Genetic and Epigenetic Factors in Cell Fate Decisions in Populations of Multipotent Stem Cells
… of key genes. The second model focused on Neural Mesodermal Progenitors (NMPs), a bipotent cell population found in the Caudal Lateral Epiblast (CLE) of mammalian embryos, which contributes to the spinal cord and paraxial mesoderm. The aim here was to derive NMPs in vitro which exhibit similar …
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Molecular mechanisms of floor plate formation and neural patterning in zebrafish
… or tailbud but is dynamically expressed in the paraxial mesoderm. I used epistatic and mutant analyses to show that Mdka acts independently from these factors. This indicates a novel mechanism of Mdka dependent MFP formation during zebrafish neurulation. To get insight into the signaling …
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Die Rolle von cDermo-1 und cTwist im Vogelembryo
… <br> <br>1) The induction of cTwist in the paraxial mesoderm of the chick embryo is dependant upon signals emanating from the axial organs. Barrier insertion results in loss of this expression. This effect was rescued by combination of Shh and FGF-8. Furthermore, we could show that the …
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Redefining the Gastrula Organiser in Early Chick Embryo Development
… AP patterning, yet the node-derived axial mesoderm retains the ability to induce distinct types of neural tissue found along the AP axis. In other model organisms, the absence of axial mesoderm disrupts forebrain development, suggesting that it plays an important patterning role. Single …