Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"parasitic protozoa"”.
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Phosphorus-31 NMR Spectroscopy of Parasitic Protozoa
31P NMR spectra have been obtained of various parasitic protozoa including Trypanosoma cruzi, Leishmania major, Trypanosoma brucei, Plasmodium berghei, Toxoplasma gondii, and Cryptosporidium parvum. The unifying features of solution-state 31P NMR spectra of acid extracts of these parasites were …
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Applications of in Vitro Cultivation Systems for Plasmodium Falciparum in the Identification and Partial Characterization of Potentially Protective Exoantigens
… widespread and pathogenic of four species of parasitic protozoa which cause malaria in humans. Comprehensive studies on the immune response to malaria, and development of effective insecticides, drugs and vaccines are of paramount importance for controlling this dreaded disease.
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Analysis of a trichomonas vaginalis cysteine protease
… because of their role in virulence of other parasitic protozoa. Determining their location and function will provide insight about their role in the pathogenicity of T. vaginalis and their feasibility as a drug target. This study begins to characterize the first sequenced cysteine protease …
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Novel Design Strategy for Potent and Selective CDPK1 Inhibitors for Cryptosporidiosis
… Cryptosporidium parvum (Cp) and C. hominis, the parasitic protozoa accountable for life-threatening diarrhea in young children and immunocompromised individuals worldwide. The unmet clinical need for the treatment of cryptosporidiosis due to the shortage of effective therapeutics has provoked the …
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Small molecules with anti-trypanosomal and anti-leishmanial activity
Parasitic diseases such as Human African Trypanosomiasis (HAT), Chagas disease and Leishmaniasis cause thousands of fatalities each year. Current chemotherapy is based on drugs discovered over 60 years ago that are expensive and difficult to administer. The drug-pipeline is virtually dry and the …
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Synthesis of thiohistidines and its metabolic pathway precursors
… biosynthesized by actinomycetes, fungi and many parasitic protozoa, respectively. Actinomycetes such as Mycobacterium tuberculosis produce mycothiol and ergothioneine as their principal low molecular mass thiols. It is only very recently that the link between ergothioneine and tuberculosis …
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Systems biology approaches to the computational modelling of trypanothione metabolism in Trypanosoma brucei
… been identified as an essential compound for parasitic protozoa, however the underlying metabolic processes are poorly understood. Structural modelling allows the study of the network metabolism in the absence of sufficient quantitative information of target enzymes. Using this approach we …
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Bioinformatics Analysis and Annotation of Microtubule Binding and Associated Proteins (MAPs) - Creating a Database of MAPs
… and associated proteins (MAPs). Infection by parasitic protozoa causes incalculable morbidity and mortality to humans and agricultural animals. In this research, we have also focused on MAPs in parasitic organisms of the Apicomplexan and Trypanosomatid genera. The protocol for analysis …
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Composition and Dynamics of the Plasma Membrane of Entamoeba Histolytica
<p>The study of the parasitic protozoa presents a multifaceted opportunity for biological research. These organisms are eucaryotic cells with many of the biological systems described in higher eucaryotic cells. However, they are adapted to highly specialized environments, invoking sometimes subtle …