Global ETD Search
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Showing 1 to 3 of 3 for “"paraptosis"”.
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Nutlin-3 sensitizes cancer cells to bortezomib via induction of paraptosis-associated cell death
… cancer cells to bortezomib via induction of paraptosis-like cell death. We found that the combined treatment yielded in MCU channeled calcium increase. This is supported with inhibition of MCU by Ru360 or knockdown of MCU significantly attenuated the cell death by the combined treatment. We …
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Celastrol induces paraptosis-like cell death via mitochondrial Ca2+ overload in breast cancer cells
… for inducing non-apoptotic cell death. Paraptosis is a kind of non-apoptotic cell death and characterized by extensive vacuolization due to dilation of mitochondria and the endoplasmic reticulum (ER). However, the regulatory mechanisms that control paraptotic events are not yet fully …
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CDDO-ME induces apoptosis in breast cancer cells via Ca2+ influx-mediated dilation of endoplasmic reticulum and c-FLIP downregulation
… on breast cancer cells 13 2.CDDO-ME induces paraptosis-like cellular vacuolation prior to morphologies features of apoptosis in breast cancer cells 17 3.Ca2+ influx is crucial for CDDO-ME-induced vacuolation and subsequent apoptotic cell death 40 4.Cross-modulation between Ca2+ influx and ROS …