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Showing 1 to 2 of 2 for “"paraneoplastic opsoclonus-myoclonus ataxia (POMA)"”.
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Nova Regulation of Alternative Splicing in the CNS
<p>Nova-1, an autoantigen in paraneoplastic opsoclonus myoclonus ataxia (POMA), a disorder associated with gynecologic cancer and CNS motor dysfunction, is a neuronspecific nuclear RNA binding protein. The work presented here confirms that Nova-1 acts as a regulator of alternative splicing in vivo. …
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The Paraneoplastic Antigen Nova-1 is a Neuron Specific and Sequence Specific RNA Binding Protein
… is recognized by sera from (7/7) patients with paraneoplastic opsoclonus-myoclonus ataxia (POMA). The gene, Nova-1, encodes a novel nuclear RNA binding protein (RBP) that is extremely highly conserved (99% amino acid identity) between human and mouse. Nova-1 is normally expressed only within …