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Showing 1 to 5 of 5 for “"para-Aminosalicylic acid"”.

  1. SPECTROFLUOROMETRIC INVESTIGATION OF THE EXCITED STATE PROPERTIES OF PARA-AMINOSALICYLIC ACID AND ITS DERIVATIVES

    CANCELLA, SHEILA DOYLE

    unh-thes Repository record

  2. The mechanistic basis of susceptibility and resistance to the antitubercular drug para-aminosalicylic acid

    Kordus, Shannon2019

    … causes severe side-effects. The antimicrobial para-aminosalicylic acid (PAS) is used to treat drug-resistant M. tuberculosis infections. Despite the use of PAS to treat M. tuberculosis for over 70 years, the biochemical mechanisms which govern PAS susceptibility and resistance in M. …

    umn Repository record

  3. Pathological and therapeutic investigations in tuberculosis: PART I PATHOLOGICAL INVESTIGATION - an investigation into hypersensitivity in tuberculosis as illustrated by the response of the skin, and of the leucocytes of the blood to tubérculin; PART II THERAPEUTIC INVESTIGATION - a clinical evaluation of the use of para-aminosalicylic acid in the treatment of pulmonary tuberculosis.

    Donaldson, Rose Isabella LyallThe University of Edinburgh1949

    PART I PATHOLOGICAL INVESTIGATION - (a) The disintegration of the neutrophil polymorphnuclear cells of the blood of a tuberculous individual is accelerated (when clotting is prevented.) in vitro by the addition of tuberculin.

    edinburgh Repository record

  4. Metal complexes of anti-tubercular drugs

    Dauda, Khadijah TolulopeDepartment of Chemistry2018

    … drugs isoniazid (ISO), ethambutol (EMB), para-aminosalicylic acid (PAS), rifampicin (RFN) and pyrazinecarboxamide (PZA) were used in this study. Since the solubility and hence permeability and bioavailability of the drugs depend on their solution speciation, the equilibrium constants for …

    cape-town Repository record

  5. Development and validation of selective and sensitive LC-MS/MS Methods for determination of para-aminosalicyclic acid and cycloserine/terizidone applicable to clinical studies for the treatment of tuberculosis

    Smit, Michiel JohannesDivision of Clinical Pharmacology2018

    A method was validated for the quantification of para-aminosalicylic acid (PAS) in human plasma. The technique consisted of a protein precipitation extraction, followed by high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS) detection. Rilmenidine was used as the internal …

    cape-town Repository record