Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 20 for “"pandemic preparedness"”.
-
Market incentives for pandemic influenza vaccines
… individuals could perish if a virulent influenza pandemic were to occur. In wake of the 2009-10 H1N1 pandemic and in an era of economic austerity, however, industry lacks clear incentives to invest in vaccines for other high-risk strains. The cyclic nature of pandemics also means we can expect …
-
Learning from pre-pandemic data to design and test future-proof therapeutics
Effective pandemic preparedness relies on predicting immune-evasive viral mutations to enable early detection of variants of concern and design vaccines and therapeutics that are resilient to future viral evolution. However, current strategies for viral evolution prediction are not available early …
-
High-throughput profiling of viral class I fusion proteins via mammalian antigen display
Viral infections, particularly epidemics and pandemics, pose a significant threat to global health, causing substantial morbidity, mortality, and socioeconomic disruption. Moreover, viruses can cause chronic disease long after initial infection. While modern technologies enable early outbreak …
-
High-throughput profiling of viral class I fusion proteins via mammalian antigen display
Viral infections, particularly epidemics and pandemics, pose a significant threat to global health, causing substantial morbidity, mortality, and socioeconomic disruption. Moreover, viruses can cause chronic disease long after initial infection. While modern technologies enable early outbreak …
-
Integrating Pandemic through Preparedness: Global Security and the Utility of Threat
… to the widely-held view that an emerging pandemic is an imminent, albeit uncertain, event linked to global interconnectedness, pandemic preparedness has been the target of considerable political concern and economic investment. To date, there has been relatively little critical research …
-
Learning from pre-pandemic data to forecast viral antibody escape
Effective pandemic preparedness relies on anticipating viral mutations that are able to evade host immune responses in order to facilitate vaccine and therapeutic design. However, current strategies for viral evolution prediction are not available early in a pandemic – experimental approaches …
-
Supply chain coordination and influenza vaccination
… of dollars are being allocated for influenza pandemic preparedness in an attempt to avert even greater potential losses. Vaccination is a primary weapon for fighting influenza outbreaks. The influenza vaccine supply chain has characteristics that resemble the Newsvendor problem, but possesses …
-
Advancing Pandemic Response: Integrated Strategies for Testing, Prediction, and Bias Mitigation
<p>The COVID-19 pandemic, along with prior outbreaks such as SARS and Ebola, has revealed critical gaps in global pandemic preparedness, emphasizing the need for integrated approaches to infectious disease management. This dissertation addresses three key areas of pandemic response: developing …
-
New-generation individual based models for infectious diseases transmission
… Health for assessing the efficacy of the Italian pandemic preparedness plan and for planning the mitigation strategies for the 2009 A(H1N1) influenza pandemic.
-
Characterization of influenza A virus evolution in laboratory hosts
… ability to predict influenza evolution and our pandemic preparedness.
-
Defining the Influence of Host Cell Proteostasis Networks and Temperature on Influenza Evolution
… vaccine and drug development as well as pandemic preparedness.
-
Studies on severe acute respiratory syndrome coronavirus type -2 in Northern South Africa
… different populations in Africa. As the COVID-19 pandemic progressed across the globe, wastewater-based epidemiology (WBE) was proposed as an alternative tool for assessing and monitoring the occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the community level. …
-
THE ROLE OF CORONAVIRUS - HOST CELL MEMBRANE INTERACTIONS DURING VIRAL ENTRY AS MEDIATED BY CONSERVED REGIONS OF THE FUSION PEPTIDE
… CoV in 2012, and the ongoing SARS-CoV-2 COVID19 pandemic, has highlighted the urgent need for a deeper understanding of coronavirus entry mechanisms to better predict and prevent future variants and pandemics. Central to viral entry is the binding and fusion of the virus with the host cell …
-
Determinants of compliance to Covid-19 standard precaution at a rural institution of higher learning in Limpopo Province, South Africa: retrospective study
… culturally appropriate communication and pandemic preparedness in rural higher education settings.
-
Informing public health policy and practice in populations with diverse needs
… health policy, which will be used in future pandemic responses in NSW. One component of the ‘The health of Aboriginal people of NSW: Report of the Chief Health Officer 2012’ is presented as the second project. The report provides baseline measurements on the health status of Aboriginal people …
-
The Impact of the COVID-19 Pandemic on Young Adult Mental Health
Before the COVID-19 pandemic, research on the mental health effects of infectious disease outbreaks was notably scarce. Addressing this gap, this thesis uses three complementary studies to explore how young adults responded and adapted to the pandemic’s challenges, with a particular focus on …
-
Host and viral determinants of flavivirus emergence and pathogenesis
… here highlight the role of basic virology in pandemic preparedness. Such studies characterizing flavivirus evolution, emergence, and pathogenesis strengthen the field’s capacity to predict and respond to arboviral threats.
-
Allocating Scarce Resources: Modeling and Optimization
… model to describe the dynamics of the COVID-19 pandemic in Greece, placing particular focus on the testing procedures. We fit the model to detailed data to quantify the overall effectiveness of the program in reducing hospitalizations and deaths, and also to understand the effects of several …
-
PHARMACEUTICAL PATENTS AND ACCESS TO MEDICINES IN GLOBAL PANDEMICS. MUTUALLY EXCLUSIVE OR MUTUALLY REINFORCING? A POST COVID-19 INQUIRY INTO THE TRIPS AGREEMENT AND HUMAN RIGHTS.
… alla salute pubblica consiste in un nuovo virus pandemico globale, rimangono largamente inesplorati. Questa tesi combina un’analisi giuridica con un’analisi della letteratura economica, di analisi economica del diritto, ed epidemiologica rilevanti per rispondere alla domanda fondamentale se …
-
Influenza Modeling, New York City, January 2000 to March 2010
… 2007 to December 2008 and to study the H1N1 2009 pandemic in relation to seasonal influenza during the period of January 2002 to February 2010. The optimal modeling technique was also studied for the feasibility to develop backcasts for January 2000 to December 2001 in hopes of further developing …