Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"pancreatic intraepithelial neoplasia"”.
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Sensitivity and Specificity of Detecting Premalignant Pancreatic Lesions by Hyperpolarized Magnetic Resonance
<p>Early detection of pancreatic ductal adenocarcinoma (PDAC) is challenging due to asymptomatic nature and deep location of the malignancy within the abdomen. The development of PDAC consists of three different pathways but two arise from the duct, Pancreatic Intraepithelial Neoplasia (PanIN) and …
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The role of tissue-resident immune cells in PanIN to PDAC progression
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer deaths worldwide. PDAC is recalcitrant to current immunotherapies, largely due to local suppression of anti-tumour immunity. Tissue-resident group 2 innate lymphoid cells (ILC2) are emerging as important immune …
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Integrin alpha6beta4 contributions in pancreatic adenocarcinoma
Pancreatic adenocarcinomas are among the most lethal human cancers due to an elevated incidence of tumor cell invasion and metastasis for reasons that are currently unclear. In this dissertation, I determined how the pro-invasive integrin alpha6beta4 expression was related to pancreatic …
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Functional contribution of epithelial to mesenchymal transition program on KRASG12D targeting efficacy in pancreatic cancer
… on KRAS<sup>G12D</sup> targeting efficacy in pancreatic cancer</strong></p> <p>Ana S. Maldonado, BS</p> <p>Advisory Professor: Raghu Kalluri, M.D., Ph.D. </p> <p>Pancreatic Ductal Adenocarcinoma (PDAC), a highly aggressive, metastatic, and therapeutically resistant form of pancreatic cancer …
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Promoter-level transcriptome identifies stemness associated with relatively high proliferation in pancreatic cancer cells
付記する学位プログラム名: 充実した健康長寿社会を築く総合医療開発リーダー育成プログラム
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Anti-Cancer Effects Of Garcinol In Pancreatic Cancer Transgenic Mouse Model
… stage. According to American cancer society pancreatic cancer, it has lowest survival rate in all cancer types, with less than 6% five year survival rate. Surgical resection is only possible for 20% of diagnosed cases and current chemotherapy has only 15% response rate. Even the most favored …