Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"pancreatic endoderm"”.
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BMP Signaling through BMPR1A is Required for Establishment of Pancreatic Laterality
Pancreatic development begins in the mouse, at embryonic day 8.5, as two patches within the gut tube that are located between the stomach and the duodenum. These patches begin to bud, proliferate, and differentiate to become the dorsal and ventral pancreas. During pancreatic bud development several …
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From Bud to Organ: An In Depth Analysis of the Development of the Pancreas.
… a careful analysis of different aspects of pancreatic development was conducted in order to expand our understating of the biology of this organ. This thesis encompasses an in depth description of pancreas macro morphology throughout development as well as the analysis of the role of …
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The role of transcription factor GATA6 in the development of the human pancreas
… for discrepancies between mouse and human pancreatic development and diseases and highlight the fact that developmental studies of the pancreas in humans are imperative. The need to develop therapies for diabetes, a growing and one of the leading health problems worldwide, further compels …
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FGF signaling in specification of hESC-derived definitive endoderm
… Pancreas originates from the definitive endoderm (DE), one of the three germ layers. The path from definitive endoderm to pancreatic progenitor cells and finally the insulin producing beta cells involves sequential cell-fate decisions characterized by the expression of multiple …
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Human Embryonic Stem Cells - Constitutive Gene Expression and Differentiation Towards Definitive Endoderm and Posterior Foregut Endoderm
… research tools. Identification of definitive endoderm (DE) - from where pancreas originates, requires analysis methods that can detect multiple markers within individual cells, since many markers expressed in DE are also detected in extraembryonic endoderm. In this thesis, we approached single …