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Showing 1 to 2 of 2 for “"pancreatic agenesis"”.

  1. The role of transcription factor GATA6 in the development of the human pancreas

    … for discrepancies between mouse and human pancreatic development and diseases and highlight the fact that developmental studies of the pancreas in humans are imperative. The need to develop therapies for diabetes, a growing and one of the leading health problems worldwide, further compels …

    cambridge Repository record for The role of transcription factor GATA6 in the development of the human pancreas (opens in a new tab)

  2. Primate-specific KRAB zinc finger proteins and their targets rewire regulatory networks related to inflammation and pancreas development

    … homozygous knock out in patients diagnosed with pancreatic agenesis, presenting neonatal diabetes with insufficient pancreatic exocrine function. Expression and ChIP data for ZNF808 show that it is upregulated during the early stages of pancreatic development and binds on members of primate …

    cambridge Repository record for Primate-specific KRAB zinc finger proteins and their targets rewire regulatory networks related to inflammation and pancreas development (opens in a new tab)