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Showing 1 to 1 of 1 for “"pair hidden Markov models"”.

  1. Statistical analysis of short template switch mutations in human genomes

    Many complex rearrangements arise in human genomes through template switch mutations, which occur during DNA replication when there is a transient polymerase switch to an alternate template nearby in three-dimensional space. These variants are routinely captured at kilobase-to-megabase scales in …

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