Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"paediatric brain tumour"”.
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Novel Diagnostics and Therapeutic Approaches for Supratentorial Ependymoma
Ependymoma is the third most common paediatric brain tumour. These tumours are incurable in up to 40% of cases. Previously classified as a single disease by histological criteria, ependymomas are now grouped into nine molecular subgroups, three in each compartment of the central nervous system. The …
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Mechanisms of medulloblastoma vulnerability and new targeted therapies
Medulloblastoma (MB) is the most common malignant paediatric brain tumour accounting for about 20% of all childhood brain cancers. Over the last decade, a consensus has been reached over the existence of 4 main molecular subtypes, known as WNT-activated MB, SHH-activated MB, group 3 MB and group 4 …
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Medulloblastoma: New animal models, preclinical drug testing, and characterising immune infiltrates
Medulloblastoma is the most common malignant brain tumour in children. The current treatment for medulloblastoma consists of surgery, radiation, and chemotherapy. Although these therapies have their merits, the outcome for some patients, particularly those with MYC amplified tumours, is poor, and …