Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 624 for “"paediatric"”.
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Paediatric Dexmedetomidine Pharmacology
… adrenoceptor agonist. Use is increasing in the paediatric setting, but without the concomitant understanding of the pharmacokinetics and pharmacodynamics to ensure safe and effective dosing. In this thesis the pharmacokinetics and pharmacodynamics of dexmedetomidine in children after cardiac …
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Paediatric nurses’ and parents’ perceptions of busyness in paediatric acute care: an ethnography
… construct within therapeutic relationships in a paediatric acute care setting or how cultural dimensions of paediatric nursing fosters perceptions of busyness within everyday care practices. 𝗔𝗶𝗺: To explore a notion of busyness within the context of paediatric acute care and how this influences …
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Novel immunotherapy for paediatric cancers
Chimeric antigen receptors (CAR) are synthetic receptors that redirect T lymphocytes to specific tumour antigens. CART cells targeting CD19 (CAR19) have demonstrated remarkable efficacy against B cell malignancies in clinic. Currently used methods of CAR gene transfer to T cells based on viral …
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Sedation in paediatric intensive care
Paediatric intensive care is an expanding specialty that has been shown to improve the quality of care provided to critically ill children. An important aspect of the management of critically ill children includes the provision of effective sedation to reduce stress and anxiety during their stay in …
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Drug recovery in paediatric tuberculous meningitis
… study design at a university-affiliated paediatric hospital in Cape Town. Patients were treated with standard TB drug regimens. Sampling was performed after standard drug administration. Blood samples were taken from routine procedures or long lines or arterial lines. LCSF was sampled …
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Aspects of paediatric gastro oesophageal scintigraphy
… scintigraphy in studies of foregut motility in paediatric patients; notably oesophageal transit during swallowing, gastro oesophageal reflux (GOR) and stomach emptying as measured by the gastric contents 30 and 120 minutes after deglutition of liquid. Relevant anatomy, physiology, …
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Paediatric asthma and wheeze: early life origins
… thesis explored the early life origins of paediatric asthma and wheeze in a large, prospective mother-child cohort. In particular, the contributions of maternal nutrition, and fetal and postnatal growth were assessed.<br/>The mothers of healthy, term infants had their body composition, …
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Family experience after paediatric acquired brain injury
This thesis explores family experiences after paediatric Acquired Brain Injury (ABI). ABI can result in physical, cognitive and psychological difficulties (Royal College of Physicians& British Society of Rehabilitation Medicine, 2003). Given its wide-ranging impact, ABI is likely to have an effect …
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Magnetic Resonance Imaging in Paediatric Coronary Vasculopathy
Background Coronary Allograft Vasculopathy (CAV) is the leading cause of late death for children after heart transplantation. It often presents late due to lack of ischaemic symptoms from the denervated allograft and it is difficult to detect using conventional angiography. A non-invasive …
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Telephone Advice and Triage within Paediatric Oncology.
… particular interest to the author who works in a paediatric Oncology Unit which is the principal treatment centre for children’s cancers within the Merseyside and Cheshire Cancer Network. This Unit provides 24 hour telephone advice for patients, families and carers. In addition, professionals …
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Ventilator associated pneumonia in major paediatric burns
Includes abstract. Includes bibliographical references.
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Somatic mosaicism in development and paediatric cancer
… potential as an underappreciated cause of paediatric malignancy. First, I use whole genome DNA and methylation sequencing of single cells derived from all germ layers to uncover the dynamics of early embryonic cell divisions in normal human development. Next, I turn my focus to two examples …
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Optimizing learning & teaching on paediatric ward rounds
… medical trainees working in the Department of Paediatrics at Princess Maria Hospital in order to enhance their self-efficacy beliefs regarding their ability to provide paediatric patient care. Specifically, we utilized a threepronged approach to 1) improve trainees' participation in, and sense …
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Paediatric Inflammatory Bowel Disease Nurses’ Experiences of using the Paediatric Inflammatory Bowel Disease Patient Held Record in Clinical Practice.
Background The Paediatric Inflammatory Bowel Disease Patient Held Record (PIBDPHR) is a tool that was initially conceptualised to enhance the care and education of children with IBD attending Alderhey Children’s Hospital. The PIBDPHR was adopted as a national project by the RCN/BSPGHaN Paediatric …
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Epigenetic silencing of gene expression in paediatric astrocytoma
… little is known about DNA methylation changes in paediatric astrocytoma. Recent investigations suggest that many tumours are initiated not only by genetic abnormalities, but also caused by epigenetic changes. DNA methylation is a key epigenetic mechanism that controls the regulation of gene …
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A social history of paediatric nursing 1920-1970
This is a study concerning the social history of paediatric nursing between 1920 and 1970. Oral history data was collected from past nurses of children and from people who had been in hospital as children within the period in question. The study explores the professional orientation of nurses and …
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Adherence to paediatric antiretroviral therapy in South Africa
Hintergrund. Die Zahl der HIV-infizierten Kinder, die in Südafrika mit antiretroviralen Medikamenten behandelt werden, steigt drastisch. Das korrekte Befolgen der Therapie (die sogenannte Adhärenz) ist ein Schlüsselfaktor für deren Erfolg. Diese Studie untersuchte die Adhärenz von jungen ambulanten …
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The molecular genetic investigation of paediatric liver disease
… of liver disease pathogenesis. As a paediatric hepatologist I have identified cohorts of children in whom there is paucity of knowledge about the disease pathogenesis. I have studied three conditions in detail to encompass different clinical presentations. Chapter 3 summarises the …
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