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Showing 1 to 3 of 3 for “"pUL21"”.
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Structural and functional characterisation of pUL21, an α-herpesvirus phosphatase adaptor protein
… different subcellular compartments. HSV-1 pUL21 is an example of such multi-function protein: it is known to be important for assembly of new virus particles and viral cell-to-cell spread but its exact molecular functions remained unknown. Using a high throughput interactomics screen, …
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Mechanisms of cell adhesion regulation by herpes simplex virus
… remodel the host cell. Three such proteins are pUL21, pUL7 and pUL51. pUL21 is a viral phosphatase adapter. pUL7 and pUL51 form a complex that localises to juxtanuclear membranes and sites of cell-matrix adhesion termed focal adhesions. All three proteins are required for efficient virus …
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Multi-modal imaging of herpesvirus infection
… analysis offer insight into the roles of pUL16, pUL21, pUL34, VP16, and pUS3 in HSV-1 nuclear egress, and the roles of pUL11, VP16, pUL51, gK, and gE in cytoplasmic envelopment. Furthermore, this analysis indicates that envelopment occurs by budding of tegument-associated capsids into …