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Showing 1 to 1 of 1 for “"pSIN-beta plasmid"”.
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The antitumor activity of tumor-targeted RNA replicase-based plasmid DNA
… we propose to deliver a RNA replicase-based plasmid DNA, hypothesizing that the dsRNA generated by the replicase-based plasmid in tumor cells will inhibit tumor growth. We evaluated the anti-tumor activity of a plasmid (pSIN-beta) that encodes the sindbis RNA replicase genes in mice with …