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Showing 1 to 1 of 1 for “"pH and Tumour microenvironment"”.

  1. A dissection of class I phosphoinositide 3-kinase signalling in mouse embryonic fibroblasts and prostate organoids

    Sadiq, Barzan A.University of Cambridge2018

    Class I PI3Ks are a family (α, β, δ and γ) of ubiquitous lipid kinases that can be activated by cell surface receptors to 3-phosphorylate PI(4,5)P2 (phosphatidylinositol(4,5)-bisphosphate) and generate the signalling lipid PI(3,4,5)P3. The PI(3,4,5)P3 signal then activates a diverse collection of …

    cambridge Repository record