Global ETD Search
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Showing 1 to 2 of 2 for “"p75 cleavage"”.
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Targeting LEDGF/p75 to Sensitize Chemoresistant Prostate Cancer Cells to Taxanes
… Lens epithelium-derived growth factor p75 (LEDGF/p75) is a stressresponse protein that promotes cellular survival against environmental stressors, including oxidative stress, radiation, and cytotoxic drugs. It is overexpressed in PCa and other cancers and has been associated with …
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The Effects Of Oxidative Stress On P75ntr Signaling In Dopaminergic Neurons
<p>The p75 neurotrophin receptor (p75NTR) is responsible for implementing cellular death during embryonic development and in response to cellular injury. The receptor has been recognized as a contributor of neurodegeneration in numerous pathological conditions. Cleavage of p75NTR by Tumor Necrosis …