Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"p66Shc"”.
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The Role of p66Shc in Stem Cells: Signalling, Identity and Apoptosis
… p46Shc act as Ras–MAPK transducers, the longer p66Shc isoform harbours an additional CH2 domain that confers distinct regulatory properties. Despite long-standing associations with oxidative stress and apoptosis, the physiological roles of p66Shc in stem cells remain poorly defined. This thesis …
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Rol de la testosterona y su receptor frente a la apoptosis en células musculares esqueléticas murinas
… con H2O2, se observa la fosforilación de JNK, p66Shc y p53, estas últimas mostrando un pico máximo de activación a la 1-2 hs. A tiempos más largos de exposición al agente apoptótico (4 hs) se produce la defosforilación de ERK2, Akt y Bad, se mantiene la fosforilación de JNK, disminuye la …