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Showing 1 to 1 of 1 for “"p53 aggregate"”.
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Characterisation and Detection of P53 Aggregates
P53 is a tumour-suppressing protein whose primary function is to protect the integrity of the genome, specifically by regulating DNA repair, cell cycle arrest, cell proliferation, and apoptosis. Wild-type (WT) p53 has multiple aggregation-prone regions and can form amyloid aggregates. Some mutants …