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Showing 1 to 1 of 1 for “"p53; tumour suppressor; cancer"”.
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An investigation of mutant p53 function.
The TP53 tumour suppressor gene is mutated in approximately 50% of all human cancers. The majority of these mutations are missense mutations resulting in the expression of a mutated form of the full-length p53 protein. This mutant protein exhibits a loss of tumour suppressive activity, …