Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 15 of 15 for “"p47"”.
-
Characterization of an Aptamer Targeting the p47/p97 Complex for Therapeutic and Diagnostic Applications in Neurodegenerative Disorders and Cancer
… modulation, this work targets the p97 cofactor p47, which directs p97 to membrane fusion processes. Using capture-SELEX, an aptamer with high affinity and specificity for p47 was identified. ITC revealed micromolar binding affinity, while NMR spectroscopy localized the interaction to the SEP …
-
Molecular Cloning of Avian Sarcoma Virus CT10 and Characterization of its Protein Product
… gag-fusion polypeptide of 47 kilodaltons, termed p47<sup>gag-crk</sup>. This protein contains blocks of sequence similarity to a noncatalytic, potentially regulatory region found in the nonreceptor tyrosine kinases, a phosphoinositide-specific phospholipase C, and the ras GTPase activator protein; …
-
Identification and Mapping of Resistance to Puccinia striiformis and Puccinia triticina in Soft Red Winter Wheat
… and Virginia) in a Pioneer ‘25R47’ /‘Jamestown’ (P47/JT) population composed of 186 F5:9 recombinant inbred lines (RILs). Analysis of the P47/JT population identified two quantitative trait loci (QTL) for leaf rust resistance on chromosome 5B and two QTL for stripe rust resistance on chromosomes …
-
NADPH oxidase in PC12 cell differentiation and apoptosis
… with subsequent recruitment of Nox1 and p47-phox during the later stages of differentiation. NGF withdrawal led to an increase in Nox1, p47-phox and p67-phox suggesting a role for those subunits in PC12 cell apoptosis. Therefore, these data confirm and extend previous results that suggest …
-
EFFECT OF DIETARY GLYCOMACROPEPTIDE AND CHOLESTEROL ON CORTICAL GANGLIOSIDE- AND GLYCOPROTEIN-BOUND N-ACETYLNEURAMINIC ACID IN YOUNG RATS
… The pups were sacrificed between P38 and P47, 14 days after the initiation of the sialic acid-supplemented diets. On the day of sacrifice, pups were decapitated and their brains immediately frozen on dry ice. Gangliosides and glycoproteins were extracted from the cortex and the sialic acid …
-
Molecular analysis of vesicle biogenesis during autophagy
… The human homologues of Cdc48 / Shp1 p97 / p47 are involved in human mitotic Golgi reassembly. This p97 / p47 complex is thought to extract a monoubiquitylated fusion inhibitor out of membranes and thereby mediate fusion. In this study the involvement of monoubiquitin in PMN as well as …
-
An Investigation of the SHIV reservoirs in the lymphoid organs of HIV-vaccinated rhesus monkeys after SHIV challenge
… at termination of vaccine group (P4, P11, P25, P47, P52) and control group (P67, P70, P71, P72) macaques were processed for determination of viral RNA and proviral DNA loads, and HIV-1 Env amino acid sequences using single genome amplification (SGA) sequencing method. In addition, cryopreserved …
-
A novel developmental rodent model to investigate the neural basis of episodic memory
… episodic memory development to overnight between p47 and p48. Immunohistochemistry allowed the investigation of the anatomical locus of the episodic memory task, and showed subtle increases in the CA3 in p48 rats. It was concluded that rats do show a similar ontogenic profile of memory as humans, …
-
Cofilin-actin rods: quantification and comparison to tau pathology in a human longitudinal aging study and developing probes to measure localization and activity of NADPH oxidase 2, a component of the prion-dependent rod inducing pathway
… we sought to develop the sensitive NOX probes, p47-roGFP and NOX-2-redtrack. These probes will give us new tools to analyze the effects that NOX activity and expression have on rod formation. The adenoviral constructs for expression of these two probes have been made and characterized within …
-
IFN-γ-vermittelte Infektabwehr von <i>Toxoplasma gondii</i> in murinen Skelettmuskelzellen <i>in vitro</i>
… ist die Aktivierung der IRG-Proteine (p47-GTPasen) beschrieben. In IFN γ-stimulierten SMZ und Fibroblasten findet eine gesteigerte Transkription der IRG-Gene Irga6 und Irgm3 in vitro statt. Außerdem wurde die Anlagerung von Irga6 auf der PVM in infizierten permanenten SMZ nach IFN …
-
Expression und Funktion des Apoptose-assoziierten Moleküls PHLDA1 im humanen Melanom
… Bei einem Gen handelte es sich um die p47- Untereinheit des humanen Translationsinitiationsfaktor eIF3, bei dem anderen Gen um das MRG-Gen (mammary-derived growth inhibitor-related gene). Translations- initiationsfaktoren werden mit der Blockade der Proteinbiosynthese während der …
-
Robert Greene's James IV : a historical approach
The purpose of this study is to point to significant historical elements of James IV that appear to be characteristic of the plays of the late sixteenth century. One major characteristic of the plays of this period is the interest shown in historical events, current and. past. Other characteristics …
-
Enhancing music-compositional flexibility
The purpose of this study is to present certain pedagogical techniques for enhancing flexibility of thinking applied to the task of writing music. The formation of pedagogical strategies was based upon ideas, derived from a review of the literature on creative thinking, which have been successful …
-
Correlates of depression following romantic breakups in adolescence
The purpose of this study was to determine if adolescents who exhibited different profiles with respect to gender and the social-cognitive variables of negative mood regulation expectancy (beliefs regarding one's ability to alleviate negative moods), self-concept, personal uniqueness (a facet of …
-
Status study and annotated directory of precollegiate instruction at National Association of Schools of Music member institutions, 1978-1979
The purpose of this study was to investigate the current programs in precollegiate instruction within the 463 Full- and Associate-member institutions of National Association of Schools of Music in the United States. A nation-wide survey was conducted in 1978-1979 to investigate the status of …