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Showing 1 to 2 of 2 for “"p38-alpha"”.
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Regulation of Mnk1 by p38α MAPK in Stress Mediated Translation Initiation
… rates for subsets of mRNAs. Both the Erk1/2 and p38 MAPK pathways activate Mnk1 meaning that Mnk1 responds to growth signals through Erk1/2 and stress signals through p38 MAPK. However, it is not clear how Mnk1 mediates translational changes specific to each pathway. We investigated the …
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G-Triple Chemiluminescent DNAZyme Based Biosensor for the Detection of Calcium(II) Ions in Solution and the Biological Functionality of Kinase Enzymes and the Rationale for their Employment as Promising Drug Targets, Substrate Specific Inhibition of P38alpha
… rooperol analogues to inhibit the protein kinase p38a. p38a is a Mitogen Activated Protein Kinase (MAPK) which when dysregulated can cause diseases such as autoimmune disorders, cardiovascular disease, inflammation, and cancer. To date, no p38a kinase inhibitor has been developed with a high level …