Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"p27 Kip1"”.
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Expression des Zellzyklus-Inhibitors p27 KIP1 in Leiomyomen und Leiomyosarkomen
… undertaken to examine the involvement of a cdkI p27KIP1 leiomyoma and leiomyosarcoma. Immunohistochemical staining was performed on 41 samples of leiomyoma and 35 samples of leiomyosarcoma and expression of p27KIP1 was evaluated semiquantitatively. The results were very inconsistent in both …
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Novel Regulation of the Cell Cycle During Cell Fate Decisions in the Central Nervous System
… promoting the degradation of the CDK inhibitor p27 Kip1 . Spy1 levels are tightly regulated during developmental processes and Spy1 upregulation has been reported in several types of cancer including human glioma. Spy1 effectors, CDK2 and p27 Kip1 , play a regulatory role in many developmental …
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The role of TNFAIP1 in regulation of LPS/TNF-ɑ-induced signaling pathway
… Claspin, Cytochromic, HO-1/HMOX1/HSP32, MCL-1, P27/Kip1, or SMAC/Diablo; 5. TNFAIP1 promoter DNA was cloned into pGL3 basic plasmid DNA to determine promoter activity. TNFAIP1 promoter activity was tested via its potential protein-protein interaction using luciferase gene expression. With a MAPK …
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Posttranscriptional gene silencing of p27 in primary prostate epithelial cells by small inhibitory RNA (siRNA)
… regulated by Cdk-inhibitors such as the p21 and p27 Cip/Kip proteins. Defects in many of the molecules that regulate the cell cycle have been implicated in cancer development. An important example is the common downregulation of the Cdk inhibitor p27 in prostate cancers. p27/Kip1 regulates the …
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Role of Cyclin-Dependent Kinase Inhibitors in Estrogen Regulation of Adipogenesis
… on the levels of cell cycle inhibitors like p27 Kip1 (p27) and p21 Cip1 (p21) in breast cancer cell lines, estrogen might have an effect on the number of adipocytes by its effect on these proteins. Lack of p27 and p21 caused obesity due to hyperplasia in mice, which led to metabolic …
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Identification of the Molecular Basis of Morphological Variation in Avian Beaks
… of its target genes, the cell cycle regulator p27(KIP1). I then identified seven mature microRNAs that appear to be specific to the avian lineage. Using PCR, I confirmed that two of these, miR-2954 and miR-2954*, are conserved across the avian lineage, from ratites to songbirds.
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Untersuchungen zur Expression der zellzyklusassoziierten Proteine p27Kip1 und Ki-67 und der Matrixmetalloproteinaseinhibitoren TIMP-1, TIMP-2 und TIMP-3 in häufigen humanen Karzinomen
… des "extracellular signaling network" dar. p27Kip1 gehört zur Familie der cyclin-abhängigen Proteinkinase-Inhibitoren und bewirkt einen Stopp des Zellzyklus in der G1-Phase. p27Kip1 gilt als Tumor-suppressor-Gen. In humanen Tumoren ist p27Kip1 häufig reduziert, was mit einer schlechteren …