Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"p22phox"”.
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Redox biology of myeloid leukaemias
… MV4-11 cells corresponds to the localisation of p22phox, a small membrane-bound subunit of NOX complex. Furthermore, we show that 32D cells, a myeloblast-like cell line transfected with FLT3-ITD, possess higher steady protein levels of p22phox than their wild type FLT3 (FLT3-WT)-expressing …
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The analysis of Bcr-Abl—Nox signalling in chronic myeloid leukaemia
… of the small membrane-bound protein p22phox, an essential component of the Nox complex. siRNA knockdown of p22phox identified it to have a significant role in cellular proliferation and cell viability, demonstrating the importance of Nox protein activity in CML disease phenotype. …
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Characterization of NADPH Oxidases in Uterine Smooth Muscle during Pregnancy
… as their regulatory subunits NoxO1, NoxA1 and p22phox were examined, including possible regulation by uterine distension and inflammation. Nox1 was prominently localized to myocyte cytoplasm, with some plasma membrane association, and significantly expressed during the contractile and labour …
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Regulation von oxidativem Stress durch biomechanische Kräfte und fettreiche Ernährung im Herz-Kreislaufsystem
… in der A. thoracalis von Nox2-/--Mäuse und die p22phox-mRNA-Expression in beiden Mausstämmen induziert. Die Analyse weiterer Organe (Herz, Niere) zeigte keine Induktion von NAD(P)H-Oxidase-Untereinheiten durch Western diet-Fütterung. Zusammenfassend sprechen die Ergebnisse der vorliegenden …
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Biological activity of anthocyanins and their phenolic degradation products and metabolites in human vascular endothelial cells
… gene expression of NOX2, NOX4, p47phox, p67phox, p22phox, & haem oxygenase-1 (HO-1), and activation/expression of p47phox and HO-1 protein; using RT-qPCR and immunoblotting (optimised for cell stimulation conditions and qPCR reference genes). Differential bioactivity of parent anthocyanins and …
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The effect of single nucleotide polymorphisms of oxidative stress genes and low grade inflammation upon pulse wave contour analysis, a useful non invasive, intermediate vascular phenotype.
… common single nucleotide polymorphisms of the p22phox gene CYBA and the endothelial nitric oxide synthase gene, NOS3, have an effect upon arterial compliance in patients with coronary artery disease (Chapters 4,5 and 6). In healthy volunteers, free of cardiovascular disease whether a …