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Showing 1 to 1 of 1 for “"p16, Rb"”.
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P16/INK4a controls the morphology program associated with cellular senescence
… <br>Results: We here demonstrate that the p16 protein controls the morphological aspects of the senescence program. Inactivation of the p16 gene in senescent human cells causes the loss of the enlarged, flattened senescent phenotype, while growth arrest remains unaffected. Instead, cells …