Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"p120-catenin"”.
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Mechanisms Regulating The P120-Catenin/Kaiso Pathway
… in cancer and developmental biology, with β-catenin being a key canonical component. P120-catenin, which is structurally similar to β-catenin, regulates the expression of certain Wnt target genes, relieving repression conferred by the POZ/ zinc-finger transcription factor Kaiso. In my first …
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P120-Catenin Regulates Rest and Corest, and Modulates Mouse Embryonic Stem Cell Differentiation
<p>The canonical-Wnt pathway and beta-catenin have been extensively studied to determine their contributions to stem cell biology, but less is known about p120-catenin in the nuclear compartment. P120 is developmentally required as a consequence of its biochemical and functional interactions with …
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A study of p120-catenin and its tyrosine phopshorylation in cancer cell adhesion and invasion
Abstract available p i.
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P120-Catenin Subfamily Members Have Distinct As Well As Shared Effects On Dendrite Morphology During Neuron Development In Vitro
… the effects of a group of four proteins – the p120-catenin subfamily – that regulate cytoskeletal remodeling and dendrite morphology. To do this, I tracked the endogenous localization of each p120-subfamily catenin during neuron development, and I determined how altering the expression of each …
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Cellular and Developmental Functions of The Xenopus Arvcf-Catenin:Kazrin Complex
Xenopus ARVCF (xARVCF), a member of p120-catenin subfamily, binds cadherin cytoplasmic domains to enhance cadherin metabolic stability, or when dissociated, modulates Rho-family GTPases. We previously found that xARVCF binds directly to Xenopus KazrinA (xKazrinA), a widely expressed, conserved …
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Structural Basis of Adhesion Activation of the Cadherin-Catenin Complex
… cytoplasmic tail. The tail is bound to alpha-catenin, beta-catenin, and p120-catenin, together known as the cadherin-catenin complex. Through alpha-catenin, the complex is connected to the cytoskeleton. Cadherins form adhesive bonds to neighboring cells through their extracellular domains. …
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Regulation of cadherin adhesion at intercellular junctions
… of a cytoplasmic binding partner, p120 catenin, increased the homophilic binding affinity of E-cadherin on Colo 205 cells. Further studies of Colo 205 cells demonstrated that four treatments, which similarly altered p120 catenin phosphorylation resulted in quantitatively similar …
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The role of PTPRF and PTPRK in regulating cell adhesion
… had previously been shown to interact with αE-catenin, a junctional plaque component. Both Afadin and αE-catenin are actin-binding proteins that are essential for cytoskeletal organisation and adherens junction regulation. We found that PTPRK competes with αE-catenin for Afadin binding when …