Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 40 for “"oxidative burst"”.
-
The effects of some antibiotics and lipopolysaccharide on oxidative burst and phagocytosis of neutrophils
The determination of phagocytosis (P) and oxidative burst (OB) in unfractionated blood is a rapid and sensitive flow cytometric method for quantifying neutrophil activation, and was modified for single laser systems by using propidium iodide labeled Staphylococcus aureus (S.aureus) as a …
-
Plant-Pathogen Interactions Associated with Wasting Disease in the Tropical Seagrass Thalassia testudinum.
… Banks ex König and was capable of inducing an oxidative burst identified at the single cell level. The formation of reactive oxygen species (ROS) included a diphenylene iodonium sensitive response, suggesting the involvement of an NADPH oxidase. A 900 bp fragment of this enzyme was sequenced …
-
Mapping PAMP Responses and Disease Resistance in Brassicas
… study (GWAS) of the flg22 and elf18 triggered oxidative bursts, resistance to Pseudomonas syringae and Botrytis cinerea was carried out in a population of B. napus. A substantial number of molecular markers, covering both sequence and expression variation, have been identified as having …
-
Neutrophil interactions with Leishmania amastigotes: implications for chronic leishmaniasis
… to infection through CD11b upregulation and oxidative burst. However, cytokine release and the ability of neutrophils to clear internalized parasites differed depending on the infecting parasite stage. Specifically, neutrophils efficiently killed promastigotes and responded to infection by …
-
Understanding the Effect of BVDV on Innate Immune Response of Neutrophils
… reactive oxygen species production (oxidative burst) and neutrophil extracellular trap (NET) formation. These studies revealed that none of BVDV strains affected the viability of neutrophils in vitro. BVDV infection did affect surface marker expression. TGAC and TGAN reduced the …
-
Copper supplementation and monocyte function in growing beef calves
… phagocytosis on d 84 and 126 and increased oxidative burst on d 42 and 126 compared to controls. Dietary Cu supplementation was repeated using 45 calves in a 120 d study. CuLy-supplemented heifers had increased major histocompatibility complex (MHC) class II expression on d 68, 82 and 110 …
-
Iron and reactive oxygen in wheat-pathogen interactions
… of attempted pathogen ingress. This so-called oxidative burst has received considerable attention, but no single enzyme has been shown to account for the phenomenon. Using inductively coupled plasma mass spectrometry and histochemistry, I show that iron is secreted to the apoplast of the …
-
Modulation of Neutrophil Functions by Neurotransmitters Implicated in Stress
… immune system. We now report that NPY modulates oxidative burst (OB) triggered by zymosan in human neutrophils while it has no effects on the phagocytosis process. NPY did not trigger but did enhance OB in a time and dose-dependent fashion. The reaction was specific since non-specific peptides …
-
The central role of the neutrophil in ischaemic/reperfusion injury
… then assessed. The genesis of an inappropriate oxidative burst by the neutrophil upon exposure to endothelial chemoattractants and adhesion molecules was also measured. Finally to appraise how tissue function might be affected by endothelial cell hypoxia the contractility of vascular smooth …
-
Survival of Salmonella in the macrophage phagosome
… One important antimicrobial defense is the oxidative burst, in which high levels of superoxide are generated within the Salmonella containing vacuole. SodCI, a periplasmic superoxide dismutase, is required to defend Salmonella against phagocytic superoxide. Work from our lab and others has …
-
Modulation of Neutrophil Functions and Anti-Tumor Immune Responses by Innate Suppressors
… and diverse functions such as degranulation, oxidative burst, and generation of extracellular trap (NET). Recent data suggest that neutrophils may also play key roles in modulating tissue inflammatory/immune environment by secreting soluble mediators as well as surface-attached co-activators. …
-
Inflamatory status and leukocyte function during the peripartum period and subsequent effects on reproduction and lactational performance in dairy cattle
… surface expression of L-selectin, neutrophil oxidative burst capacity when co-cultured with an environmental Escherichia coli, as well as the secretion of tumor necrosis factor-α and interferon-γ when diluted whole blood were co-cultured with lipopolysaccharide and phytohemagglutinin-P, …
-
Regulation of receptor kinase-mediated immune signalling by dynamic phosphorylation
… NADPH oxidase RBOHD by BIK1, leading to reduced oxidative burst and stomatal immunity. Notably, upon PAMP perception, PP2C38 is phosphorylated on serine 77, most likely by BIK1, and dissociates from the PRR-BIK1 complex. We suggest that this mechanism relieves the negative regulation imposed by …
-
Endocannabinoid and lipid metabolism genes network analysis in adipose and liver tissue of dairy cows during the transition period
… acid oxidation (CPT1A, CPT2, ACADVL, ACOX1), oxidative stress (SOD1, SOD2), and genes that are involved in inflammation (TLR9, TLR4, NFE2L2). Expression of CNR2 and NAPEPLD was greater at 7 d in LoBCS due to lower expression at the same time in HiBCS. The expression of FAAH was upregulated at …
-
Gene Regulation of Tartrate Metabolism in Salmonella typhimurium
… At later time points, a neutrophil-derived oxidative burst facilitates an oxidative central metabolism in S. Tm and represses tartrate utilization. We sought to understand how Salmonella coordinates its gene expression of carbon and energy sources as it experiences transient nutrient niches …
-
Characterizing the Role of the E. Coli Cytochrome Oxidase AppBCX During Intestinal Inflammation
… been shown to influence local oxygen levels. The oxidative burst mounted by neutrophils consumes oxygen, which in turn creates a hyper-hypoxic microenvironment. These two seemingly contradictory findings remain to be reconciled. The findings described here delineate an additional mechanism that …
-
Studies of bacterial homeostasis Sinorhizobium meliloti and Escherichia coli
… of this symbiosis, M. sativa releases an oxidative burst that S. meliloti must be able to overcome in order for symbiotic development to continue. Employing a novel two-part screen, I identified Sinorhizobium meliloti mutants that were both sensitive to oxidative stress and symbiotically …
-
IDENTIFICATIN AND CHARACTERIZATION OF PATHOGENICITY GENES IN FUSARIUM VIRGULIFORME, THE CAUSAL AGENET OF SUDDEN DEATH SYNDROME (SDS) IN SOYBEAN
… defense to phytoalexin, glyceollin and induced oxidative burst was also investigated by generating an<italic>FvΔgrx2</italic> knockout. In order to establish a link between the fungal karyotype and the level of fungal aggressiveness, the chromosome length polymorphism (CLP) was assessed for …
-
Dissection of Regulatory Networks Mediating Resistance and Susceptibility of Arabidopsis thaliana to the Downy Mildew Pathogen Hyaloperonospora parasitica
… double mutants delay, but do not suppress, the oxidative burst and the hypersensitive response. These results suggest that RPP7 activates multiple signaling pathways, each of which makes incremental contributions to the timing of defense activation. The second objective of the dissertation was …
Page 1 of 2