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Showing 1 to 3 of 3 for “"oxidation of guanine"”.

  1. Singlet Oxygen Oxidation of Guanine, 9-Methylguanine and Guanine-Cytosine Base Pair: Dynamics and Kinetics Revealed by Parallel Gas- and Solution-Phase Experiments and Computations

    Lu, WenchaoThe Graduate School and University Center of The City University of New York2018

    … oxidatively generated damage of DNA gives rise to mutagenesis, carcinogenesis, and cellular death. Guanine is the most susceptible DNA target of <sup>1</sup>O<sub>2</sub>. The related process has been studied over three decades but the mechanism has remained elusive. My thesis …

    cuny-grad Repository record

  2. INFLAMMATION INDUCED CYTOSINE DEAMINATION DAMAGE IN CANCER ETIOLOGY

    Hsu, Chia WeiThe University of Texas Medical Branch at Galveston2022

    … in cancer etiology. The mutational landscape of human cancer is dominated by cytosine to thymine transition mutations, and the primary mechanism for these mutations is the deamination of cytosine and cytosine analogs to uracil and the corresponding uracil analogs. During replication, uracil …

    utmb Repository record

  3. Computational investigation of oxidative damage to guanine: formation, recognition and removal by DNA repair enzymes in humans and bacteria

    Sowlati-Hashjin, Shahin, University of Lethbridge. Faculty of Arts and Science2018

    lethbridge