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Showing 1 to 20 of 745 for “"oxidase"”.
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Aromatic alcohol oxidase, aldehyde oxidase and mannitol oxidase in terrestrial gastropods
Several unusual hydrogen peroxide generating oxidase activities have been investigated in the alimentary tissues of terrestrial gastropod molluscs. A membrane-bound aromatic alcohol oxidase activity has been demonstrated in the digestive gland (hepatopancreas) of four families of gastropod …
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Pyruvate Oxidase and the Cytochrome D Terminal Oxidase of Escherichia Coli
… electron transport system were studied, pyruvate oxidase and the cytochrome d terminal oxidase. Three general subjects were treated: (i) the active site structure and catalytic mechanism of pyruvate oxidase, (ii) the role of pyruvate oxidase in the E. coli aerobic electron transport system, and …
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Characterization of multicopper oxidase-related protein and multicopper oxidase-1 in insects
Typical multicopper oxidases (MCOs) have ten conserved histidines and one conserved cysteine that coordinate four copper atoms, which are required for oxidase activity. During our studies of insect MCOs, we discovered a gene that we named multicopper oxidase-related protein (MCORP). MCORPs share …
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Globin Oxidase and Methemoglobin Reduction
Made available in DSpace on 2014-12-05T22:14:35Z (GMT). No. of bitstreams: 1 0018179.pdf: 3120862 bytes, checksum: d39b28cec95826b80e65765af94eef48 (MD5) Previous issue date: 1956
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Studies on human protoporphyrinogen oxidase
… the effects of various protoporphyrinogen oxidase mutations responsible for variegate porphyria, the role of the arginine-59 residue, and the glycines in the conserved flavin binding site, in catalysis and/or cofactor binding. Wild type recombinant human protoporphyrinogen oxidase and a …
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Monoamine oxidase in neuronal cell death
Monoamine oxidase (MAO) is an oxidative enzyme that deaminates a variety of amine substrates, including the neurotransmitter dopamine. The enzymatic reaction requires molecular oxygen and produces hydrogen peroxide as a by-product. MAO is localised in the outer mitochondrial membrane and exists as …
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Pyruvate Oxidase: Mechanism of Lipid Activation
Made available in DSpace on 2014-12-14T04:27:40Z (GMT). No. of bitstreams: 1 7803940.pdf: 8298143 bytes, checksum: 073b2078a6d81cca2e575b541f2d2262 (MD5) Previous issue date: 1977
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Structure and Function Relationships in Cytochrome Bo(3) Oxidase and Cytochrome Bd-I Oxidase From Escherichia Coli
… and function relationships in the two terminal oxidases in Escherichia coli have been investigated. Cytochrome bo3 oxidase, a member of the heme/copper superfamily, is found to have a semiquinone intermediate during turnover of quinol. Additionally, after the quinol is consumed and turnover …
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Studies on monoamine oxidase in avian brain
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The Enzymatic Oxidation of Aldehydes by Xanthine Oxidase
… its earliest recognized action, hence xanthine oxidase. Although little is known about the biological functions of the enzyme, the high affinity shown for xanthine and hypoxanthine may indicate that these are the most significant substrates biologically.
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NADPH oxidase in PC12 cell differentiation and apoptosis
… and apoptosis. In addition, NADPH oxidase has been implicated in the differentiation and apoptosis of this cell line through production of reactive oxygen species (ROS). However, the subunits involved in both processes have not been identified. A series of studies were designed to …
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Infrared Spectroscopy of Cytochrome C Oxidase Intermediate States
Cytochrome c oxidase is a critical player in the process of cellular respiration, performing proton translocation coupled to the four-electron reduction of O2 to H2O. To accomplish this catalytic task, specific changes at the active site influence chemical and physical changes throughout the …
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Ligand-Binding Properties of Escherichia Coli Pyruvate Oxidase
Made available in DSpace on 2014-12-13T20:10:33Z (GMT). No. of bitstreams: 1 7913567.pdf: 6615798 bytes, checksum: e50e91608fa1b94872aa9b0ce11516a0 (MD5) Previous issue date: 1978
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Further Studies on Pyruvate-Oxidase of Escherichia Coli
Made available in DSpace on 2014-12-10T23:24:29Z (GMT). No. of bitstreams: 1 7317365.pdf: 5052932 bytes, checksum: 5a7a3040a6ad64e91771a4c21382558b (MD5) Previous issue date: 1972
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Studies of proton pumping mechanism in BA3 type cytochrome oxidase of thermus thermophilus and CBB3 type cytochrome oxidase of vibrio cholerae
… site. According to the crystal structure of ba3 oxidase in T. thermophilus, two highly conserved residues, D372 and H376 which are located at the interface of subunit I and II of complex, form ion pairs with the A-propionate of active-site heme a3. A set of mutations of D372 and H376 are made and …
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Circular dichroism studies of Escherichia coli pyruvate oxidase and secondary structure and lipid binding properties of the alpha peptide from pyruvate oxidase
Pyruvate oxidase, a tetrameric enzyme consisting of four identicle subunits, undergoes a change in conformation with the binding of TPP and pyruvate. Circular dichroism measurements show the change in secondary structure with this ligand induced conformational change. Circular dichroism spectra …
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The Role of NADPH Oxidase in ROS Mediated Differentiation
… was investigated and members of the NADPH oxidase (NOX) family were identified as candidates as Nox1-4 and Duox2 genes are up-regulated by RA. This study shows Nox1 and Nox4 are up-regulated when Gata6 is overexpressed in F9 cells. Furthermore, the pan-NOX inhibitor VAS2870 and …
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Mechanisms of regulation of islet function by nadph oxidase
… have shown activation of phagocyte-like NADPH oxidase [Nox] to be underlying cause for increased ROS generation observed under the above pathological conditions.</p> <p>The overall objective of the present study is to i) determine potential mechanism[s] underlying nutrient-induced generation of …
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Characterization of the Pichia pastoris alcohol oxidase I promoter
… is attributed to the highly induceable Alcohol Oxidase I promoter (AOXI). Despite of the disperse popularity and use of this promoter over the last 15 years, little is known about the transcription controls at a molecular level. A 5'>3' deletion analysis of the AOXI promoter was perrormed to …
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