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Showing 1 to 4 of 4 for “"oxadiazoles"”.

  1. Development of Novel Methods for the Installation of Trifluoromethyl/Boryl and 1,2,4-Oxadiazole Moieties

    … 5 provides insight into the synthesis of 1,2,4-Oxadiazoles which are privileged scaffolds in medicinal chemistry. The developed reaction occurs under metal-free conditions using sodium carbonate to couple N-hydroxylbenzenecarbonimodyl chlorides with nitriles.

    vt Repository record for Development of Novel Methods for the Installation of Trifluoromethyl/Boryl and 1,2,4-Oxadiazole Moieties (opens in a new tab)

  2. SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL ANTIPARASITIC AND ANTICANCER AGENTS

    … the antiproliferative effects of the oxadiazoles described in the previous part. Lastly, I moved to a target-based approach, and I selected 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB-3), which plays a key role in oncogenesis. It is a glycolytic regulatory enzyme …

    milano Repository record for SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL ANTIPARASITIC AND ANTICANCER AGENTS (opens in a new tab)

  3. Electroactive Conjugated Polymers as Charge-Transport Materials for Optoelectronic Thin-Film Devices

    … excited states. With the carbazole-substituted oxadiazoles 1–3 it was shown that on the one hand the carbazole functionality is suitable for enabling the electrochemical polymerisation of the monomers and on the other hand it facilitates reversible p-doping of the resultant polymers. Although …

    wurz-thes Repository record for Electroactive Conjugated Polymers as Charge-Transport Materials for Optoelectronic Thin-Film Devices (opens in a new tab)

  4. Chemie polynitrovaných heterocyklických sloučenin

    Byla zpracována rešerše na téma polynitrované heterocyklické sloučeniny. Jedná se o sloučeniny se schopností detonace, způsobené zejména přítomností nitroskupin, které jsou navázány na atomy uhlíku jejich cyklu. Tato práce se zabývá nejznámějšími zástupci jednotlivých skupin tohoto typu látek od …

    brno-tech Repository record for Chemie polynitrovaných heterocyklických sloučenin (opens in a new tab)