Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"overlapping functions"”.
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Multitasking for sensor based systems
… coordinate the activities of the different overlapping functions and give the user the appearance of concurrent activity. The coordination and scheduling is performed according to a user defined order of importance or priority. There are many multi tasking operating systems available for all …
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A functional analysis of Rab11a and Rab11b in endosomal recycling
… Rab11a and Rab11b have non-redundant and non-overlapping functions in the cell.
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Investigating mechanisms and biological functions of the bHLH/PAS transcription factors SIM1 and ARNT2
… studies have also indicated unique as well as overlapping functions of ARNT and ARNT2 during embryonic development. Due to the lethality of homozygous null mice, there is limited knowledge of unique and overlapping functions of these two proteins in adult tissues. The development of a …
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Examining the boundary conditions between cognitive control and interference derived from stimulus-based and response-based conflict
… a similarly defined construct that shares many overlapping functions with cognitive control. The studies presented used controlled forms of interference to identify limits, or boundary conditions, that could help clarify the relationship between cognitive control and WMC. Experiment 1 used …
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Incomplete paralog compensation and splicing regulation by TRA2A and TRA2B in cancer
… in the human genome and frequently retain overlapping functions, enabling cells to withstand the loss of one gene without compromising viability. In cancer, this functional redundancy provides resilience against genomic instability but also creates therapeutic opportunities through …
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Structure-function analysis of ZapC, an FtsZ-ring stabilizer, in Escherichia coli cytokinesis
… are recruited during early cytokinesis and have overlapping functions in stabilizing FtsZ at midcell, but share no primary sequence identity. The focus of this study is on ZapC, a small cytoplasmic protein that is conserved in the gamma proteobacteria, co-localizes with FtsZ at midcell, and …
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The Interplay of Signal Transduction and Membrane Traffic of the Macrophage Colony Stimulating Factor Receptor (MCSFR) Controls Macrophage Growth
… mice we have shown that Cbl and Cbl-b share overlapping functions in controlling MCSFR internalization, traffic to macropinosomes, degradation and ultimately cell growth. This work lays the foundation for uncovering the mechanisms of MCSFR signal regulation via endocytic traffic and creates a …
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“New People”: Memory, Leisure, and Identity at the British Seaside in Last Orders and the Remains of the Day
… “unlived life” (i) allows for analysis of the overlapping functions of memory, storytelling, and identity in both novels. While Ishiguro’s butler, Mr. Stevens, sidesteps the implications of his life so fastidiously that he has no identity outside of his work, Swift’s many narrators seem …
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Role of MOA-1, an Anti-phosphatase, and APL-1, an APP-related Protein, in Morphogenesis and Mating Behavior in Caenorhabditis elegans
… of two paralogues, APLP1 and APLP2, which have overlapping functions, the normal function of APP is difficult to elucidate. Knockout of the entire APP gene family in mice results in lethality and developmental defects, indicating that the APP gene family has an essential function. The nematode …
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Characterization of Non-Coding RNAs in Regulating Thymic Epithelial Cell Responses to Pathophysiological Stress
… long noncoding RNA, MIR205.001 in regulating TEC functions. A deficiency of miR-205 specifically in TECs renders these cells more susceptible to stress mediated thymic involution. This is revealed by a significant loss in developing thymocytes, altered migration, delayed recovery of single …
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Identification of cellular functions of cardiolipin as physiological modifiers of barth syndrome
… approaches in yeast to elucidate the cellular functions of CL. Understanding the functions of CL is expected to shed light on the pathology and possible treatments for BTHS.</p> <p>BTHS is caused by mutations in TAZ1, which encodes a CL remodeling enzyme called tafazzin. BTHS patients exhibit a …
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Substrate Interaction and Sub-Cellular Localization in Map Kinase Pathways
… ERK5 are two closely related enzymes that have overlapping functions in a number of cellular pathways. Sub-cellular localization and specificity towards substrates are two mechanisms of controlling the function of an enzyme in the cell. My dissertation discusses the insights we have gained into …
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Fancm and Faap24 Maintain Genomic Stability Through Cooperative and Unique Functions
… cells, and systematically investigated the functions of FANCM and FAAP24 inchromosome stability, FA pathway activation, DNA damage checkpoint signaling, and ICL repair. I found that the<em> FANCM<sup>-/-</sup>/FAAP24<sup>-/- </sup></em>double mutant was much more sensitive to DNA …
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The Analysis of Two Receptor-like Kinases Redundantly Required for Pattern Formation during Arabidopsis Embryogenesis
… analysis indicates that RPK1 and TOAD2 have overlapping embryonic functions. The zygotic gene dosage of TOAD2 in an rpk1 background is of critical importance, suggesting that signaling mediated by RPK1 and TOAD2 must be above a threshold level for proper embryo development. The localization …
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Molecular Characterization and Loss-of-Function Analysis of an Arabidopsis thaliana Gene Encoding a Phospholipid-Specific Inositol Polyphosphate 5-Phosphatase
… with similar substrate selectivity may have overlapping functions. In summary, the findings that At5PTase11 is a phospholipid-specific 5PTase and At5PTase11 functions in the early stages of seed germination and seedling growth indicate that 5PTases play important roles in plant growth and …
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Functional Analysis of Cytosolic Hsp70 Nucleotide Exchange Factor Networks In Yeast
… is the primary NEF contributing to most Hsp70 functions and also uncovered a unique role for Fes1 in Ssa-mediated regulation of the cytosolic heat shock response, while revealing no significant contributions from Snl1 and Sse2. These findings suggest that NEFs do have overlapping functions, but …
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Interaction of Quantal Inhibitory and Excitatory Neurotransmission in Regulation of Synaptic Homeostasis via Molecular Signaling
… at inhibitory synapses may have partially non-overlapping functions. Because the function of inhibitory spontaneous neurotransmission is largely unknown, we next examined the signaling capacity of inhibitory spontaneous neurotransmission. We discovered that modulation of inhibitory, but not …
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Functional specialization of Arabidopsis poly(A) polymerases in relation to flowering time and stress
… FLC activator. PAPS2 and PAPS4 exhibit partially overlapping functions and ensure timely flowering by repressing FLC and at least one other unidentified flowering inhibitor. The latter two cPAPs act in a novel regulatory pathway downstream of the autonomous pathway component FCA and act …
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Understanding the role of the Notch intracellular domain in transcription hub formation
… Mastermind and the NICD C-terminus may have some overlapping functions. These experiments provide new insights into the role of NICD in promoting a transcription “hub” at target loci to promote transcription. A second goal was to manipulate the timing of activation and the levels of NICD to …
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Social marketing in Aotearoa New Zealand: Analysing its evolution to inform, improve, and justify its future
… of social marketing in Aotearoa New Zealand; the overlapping functions of social marketing and public relations; and the incorporation of indigenous communities’ values into social marketing. 1. The growth and decline of social marketing In an original developmental framework for social marketing …
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