Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 365 for “"ovary"”.
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Cardiometabolic aspects of polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting 6-7% of the population. It is characterised by chronic anovulation and hyperandrogenism with the clinical manifestation of oligomenorrhoea, hirsutism and acne. A ten to twenty fold increased risk for type 2 diabetes in PCOS …
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Hormonal regulation of microRNA expression in the ovary
The ovary is a dynamic organ that is charged with the responsibility of producing a viable gamete so that the circle of life can be reproduced for future generations. The ovary is also responsible for producing, secreting, and maintaining the proper hormone milieu of estrogens and progesterone for …
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Recruitment of monocytes to the pre-ovulatory ovary
… It requires the chemotaxis of leukocytes to the ovary to help regulate and promote these events. Hormonal signals and chemokines that are released during the peri-ovulatory period initiate the release of specific leukocyte populations, possibly from the spleen, that infiltrate the ovary and …
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Micro-bioreactor design for Chinese hamster ovary cells
… for the culture of Chinese Hamster Ovary (CHO) cells. There is an increasing demand for upstream development in high-throughput micro-bioreactors specifically for the recombinant CHO cell line, an important cell line for producing recombinant protein therapeutics. In order to …
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Dysregulation in polycystic ovary syndrome: mechanisms and therapeutic approaches
Polycystic ovary syndrome (PCOS),a complex widespread hormonal disorder that affects between 8-13% of reproductive-aged women globally. It is marked by high levels of androgens (male hormones), irregular ovulation, and metabolic disorders, all of which are linked to disruptions in gonadotropin …
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Steroidogenic cell populations in follicles of the chicken ovary
… in preovulatory follicles of the chicken ovary states that the granulosa layer metabolizes cholesterol to progestins and progestins are, then, metabolized to androgens and estrogens by the theca layer. However, the precise site of steroidogenic cells in the theca layer of preovulatory …
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The effects of iodoacetic acid on the mouse ovary
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-05-01
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Genetic control of death in Chinese Hamster Ovary cultures
… cell culture systems, including Chinese Hamster Ovary (CHO) cultures, is the inability to maintain viability of these cultures over extended periods of time. This inability translates into lower final protein titers and higher protein production and recovery costs. This thesis was undertaken to …
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Ire1 regulates cyp11a1 transcription to mediate steroidogenesis in the ovary
CYP11A1 transcriptional activation in response to gonadotropin hormones is critical to maintain fertility and support pregnancy. Therefore, we are interested in identifying factors that regulate CYP11A1 transcription. Our laboratory has identified several signaling proteins that activate CYP11A1 …
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The Hormonal Regulation of the Claudin Genes in the Ovary
The ovary is a dynamic organ that responds to many hormonal signals. When these hormonal signals are disrupted, ovarian dysfunction can occur. One such example is Polycystic Ovarian Syndrome (PCOS). PCOS patients suffer from high levels of testosterone. Excess testosterone may misregulate genes in …
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Glycosylation site occupancy heterogeneity in Chinese hamster ovary cell culture
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1998.
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Towards a More Accurate Diagnosis of Polycystic Ovary Syndrome (Pcos): The Role of Anti-Müllerian Hormone and Ultrasound in Identifying Polycystic Ovary Morphology in Pcos Patients
La sindrome dell'ovaio micropolicistico (PCOS) è il disturbo endocrino più comune nelle donne in età riproduttiva, e una diagnosi accurata è cruciale non solo a causa della sua alta prevalenza, ma soprattutto per i rischi per la salute a lungo termine. Nonostante ciò, esistono ancora numerose …
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Role of the Dietitian in Multidisciplinary Treatment of Polycystic Ovary Syndrome
Background: Polycystic Ovary Syndrome (PCOS) is the most common reproductive endocrine disorder in females. Genetic and lifestyle factors influence the etiology and insulin resistance plays a key role in the pathogenesis of PCOS.;Objective: To investigate the current trends and future implications …
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Modeling the Psychiatric Aspects of Polycystic Ovary Syndrome and Induced Stress
Polycystic ovary syndrome (PCOS) is an endocrine disorder in women that is characterized by excess testosterone and is associated with increased risk of infertility. Women with PCOS also show higher rates of depression and anxiety. Modeling PCOS in mice via administration of dihydrotestosterone …
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Extraovarian and Intraovarian Control of Follicular Selection in the Chicken Ovary
… the basis for regular ovulation. In the chicken ovary, one small yellow follicle (SYF) is selected daily from a pool of similar size follicles and becomes a preovulatory follicle. Follicle stimulating hormone (FSH) and luteinizing hormone (LH) are primary regulators of follicular growth and …
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The Effects of Luteinizing Hormone on Sterol Metabolism in The Ovary
Made available in DSpace on 2015-05-13T22:12:03Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7021021.PDF: 6099438 bytes, checksum: b0d6ce4171d75c587a5966ecade01d78 (MD5) Previous issue date: 1970
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Effect of aging on metabolic status and hormone responsiveness in the ovary
There were significant effects of mares' ages on gene expression in granolosa cells. Most of the effects we noted were on the expression of AMPK subunits, italics indicating genes rather than gene protein products, although there were significant effects of animal age on GLUT4 and IGF-1R expression …
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Exploration of biological causes of psychological problems in polycystic ovary syndrome (PCOS)
Background: Polycystic ovary syndrome (PCOS) affects up to 10% of women, and is characterised by elevated testosterone (T) levels. Women with PCOS have higher scores than healthy women on a range of measures of psychological problems. Objective: To test the hypotheses that: 1/ The female fetus in a …
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