Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"ovariectomized mice"”.
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Can low-dose lithium supplementation protect against sarcopenic obesity in ovariectomized mice?
… and enhances insulin sensitivity in male mice. However, it is unknown whether GSK3 inhibition will have similar benefits in female mice in the presence and absence of estrogen. The purpose of this thesis was to investigate whether low-dose Li supplementation can protect against sarcopenic …
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Alendronate Alters Single Cell Gene Expression of Cortical Osteoblast Lineage Cells During Bone Loss
… osteoblasts derived from the femurs of C57BL/6J mice. After isolating single cells from bone, we were able to individually analyze their gene expression profiles using the quantitative polymerase chain reaction (qPCR). The mice used for the study were divided into 4 treatment groups, including …
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Tissue-Specific Mediation of Estrogen-Induced Epithelial Events by the Estrogen Receptor in Female Reproductive Tract Organs
… from ERalpha knockout (ERKO) and wild-type mice to enzymatically separate the epithelial and stromal fractions. Isolated tissue fractions were recombined to produce tissue recombinants that contained ERalpha in both epithelium and stroma or lacked ERalpha in one or both tissue compartments. …
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Antagonistic Roles of miR-199a-3p/miR-214 and the miR-200 Family in the Regulation of Uterine Contractility During Pregnancy and Labor
… coordinately decreased in myometrium of mice as they progressed to labor and in laboring myometrium from pregnant women. These changes were associated with a dramatic increase in expression and activity of 20α-HSD in laboring myometrium from mouse and human. In a progesterone-withdrawal …
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The effects of di (2-ethylhexyl) phthalate (dehp) on lesion development in a mouse model of endometriosis
… transplantation surgery. We then determined if mice with endometriotic lesions show signs of pain or discomfort using a behavioral assay. We also examined whether there is a genetic impact on the incidence and progression of endometriosis in our mouse model by comparing two different strains of …
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The Effect of Lycii Radicis Cortex Extract on Bone Formation in vitro and in vivo
… effect of LRC extract in vivo was examined in ovariectomized (OVX) mice. The OVX mice administered LRC extract for 8 weeks and 16 weeks, respectively, exhibited significantly increased bone mineral density (BMD) compared to the non-treated control OVX mice, and no toxic effects were observed. …