Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"ovarian cancer treatment"”.
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Chemotherapy-Eluting Intraperitoneal Implants for Advanced Stage Ovarian Cancer Treatment
… IP chemotherapy has improved survival in ovarian cancer (OC) patients, but its adoption has suffered due to resource requirements and dose-limiting toxicities. We previously showed that an IP device that delivers sustained low-dose chemotherapy over time is equally effective in treating OC …
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Directed Evolution of Macrocyclic Peptides For Inhibition of Autophagy
… plays an important role in the development of treatment resistance and dormancy in many cancer types. Chloroquine (CQ) and hydroxychloroquine (HCQ), two autophagy inhibitors in clinical trials, suffer from poor pharmacokinetics and high toxicity at therapeutic dosages. This has prompted intense …
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Molecular Determinants of Residual Disease In Ovarian Cancer
<p>The standard treatment for high grade serous ovarian cancer is primary cytoreductive surgery followed by adjuvant chemotherapy. Residual disease followed by surgery is associated with adverse overall and progression-free survival as well as poor response to adjuvant chemotherapy. Accurate …
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Engineering layer-by-layer nanoparticles for the targeted delivery of therapeutics to ovarian cancer
Survival rates for ovarian cancer haven't meaningfully improved in thirty years. Ovarian cancer is particularly difficult to treat because it is usually discovered after it has metastasized and it quickly develops resistance to the few drugs that are initially effective at controlling it. …
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Combination Chemotherapy and In vivo Modeling of BRCA-deficient, High-grade Serous Ovarian Cancer
Ovarian cancer is the most fatal cancer in women with over 60% of patients succumbing to the disease. Mutations in a number of homologous recombination repair genes have been implicated in hereditary ovarian and breast cancer. Specifically, over half of ovarian cancer cases exhibit BRCA-deficiency …
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Activity behavior and physiological profile of advanced-stage ovarian cancer survivors
Background: Advanced-stage ovarian cancer survivors (OCS) often experience a multitude of disease symptoms and treatment-related side-effects. Additionally, most OCS are older, have comorbidities, are overweight or obese, and report being insufficiently physically active. Ovarian cancer survivors …
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Downregulation of Pax2 Suppresses Ovarian Cancer Cell Growth
… <em>PAX2</em> has been found in several cancer types. We therefore sought to elucidate the role of PAX2 in ovarian carcinomas. We found that PAX2 was expressed in low-grade serous, clear cell, endometrioid and mucinous cell ovarian carcinomas, which are relatively chemoresistant compared …
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Ošetřovatelská péče o pacientku s diagnózou karcinom ovaria
… of case study, nursing care of the patient with ovarian cancer, 63 years old patient has been hospitalized on the clinic of gynecology and obstetric because of gynecology operation. The theoretical part deals with general introduction to the anatomy and physiology of female genital organs, here …