Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 111 for “"ovalbumin"”.
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Creation of Ovalbumin Based Scaffolds for Bone Tissue Regeneration
… many bio-based materials have been used, Ovalbumin (OA) has not yet been researched to create 3D structures that promote cellular responses. Micro-porous scaffolds are a promising construct for bone tissue regeneration; therefore OA crosslinked with three different concentrations (10%, 15% …
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Ovalbumin-Based Scaffolds Reinforced with Cellulose Nanocrystals for Bone Tissue Engineering
… to prevent immediate failure upon implantation. Ovalbumin (OVA), a glycoprotein from chicken egg whites, has been use to fabricate biodegradable, porous hydrogel bone scaffolds that promote osteoblast attachment and proliferation. Although ovalbumin scaffolds encourage bioactivity and are …
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Mechanical and Cellular Response to Biomineralization of Ovalbumin Scaffolds for Bone Tissue Engineering
Studies regarding the feasibility of ovalbumin (OVA) as a bone scaffold material have found its cost, availability, interaction with cells, and ability to degrade in the body into safe byproducts to be ideal for such an application. However, weak mechanical properties cause hesitation in the use of …
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Development of a humanised mouse model of ovalbumin induced allergy and inflammation as a platform to test functional food
Food allergies are most common during infancy Food allergy is a growing health problem with very limited treatment options For infants, cow’s milk protein allergy (CMPA) is the predominant food allergy, occurring in 2 - 7 5 % of population Infant formula which is often cow’s milk based, is the only …
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Clinical Significance of Specific IgE Antibody Levels to Egg White, Ovalbumin and Ovomucoid in Egg Allergic Children Under 24 Months
… baseline specific IgE antibodies to egg white, ovalbumin, and ovomucoid in predicting anaphylaxis, and secondly to evaluate the clinical usefulness of the specific IgE antibodies in predicting persistence of immediate-type allergic reactions in young children. METHODS: This study included 49 …
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The Administration of P2Y12 Antagonist (P113) Attenuates Airway hyperresponsiveness and Airway Inflammation in an Ovalbumin (OVA) Specific Allergic Asthma Model
Backgound and OBJECTIVE: Leukotriene E4 contributes to airway inflammation by interacting with P2Y12 receptor as well as type 1 and 2 cysteinyl leukotriene receptors. We investigated the effects of P113, a P2Y12 receptor antagonist, on airway inflammation in a mouse model of allergic asthma. …
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Generation and analysis of transgenic mice expressing ovalbumin as a neo-self antigen under control of the myelin basic protein promoter
… specifically expressing the neo-antigen (Ag) ovalbumin (OVA) in either the central nervous system (CNS) or peripheral nervous system (PNS) were to be generated. The myelin basic protein (MBP) is a major component of the myelin sheath both within the CNS and the PNS. Therefore the MBP promoter …
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Response of early weaned pigs to an escherichia coli challenge and their absorption to ovalbumin or xylose as influenced by creep feeding
… to an oral challenge of E. coll or to absorb ovalbumin or xylose was investigated. Eighty pigs (45 exposed, 35 control) were orally challenged 24 h after weaning with 3x1011 organisms of E. coli (0157 H88AC:H43); control pigs tended (P<.10) to scour more than the exposed pigs (46% vs 27%). …
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Humoral and cell-mediated immunity in vitamin A-deficient lambs
… primary and secondary antigenic challenges of ovalbumin (1mg) and lysozyme (.1mg). The A-def lambs were then repleted with vitamin A and all lambs were injected with primary and secondary antigenic challenges of human gamma globulin (HGG) (.1mg). In Trial II Con and A-def wether lambs were …
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Determining the Effects and Signaling Properties of β-Blockers in House Dust Mite-Driven Murine Models of Asthma
… required for developing the asthma phenotype in ovalbumin-driven murine models of asthma. Furthermore, our studies suggested that chronic treatment with certain β-blockers such as nadolol and ICI 118, 551 was able to attenuate the asthma phenotype in murine models. However, not all β-blockers …
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Interaction between membrane and protein properties on flux decline during sterile microfiltration
… consisted of lysozyme, β-lactoglobulin and ovalbumin. The pH values of the solution were set at the isoelectric point of each of the proteins (11.0, 5.8, and 4.7 respectively). The experiments were operated with a feed pressure of 2 or 10 psi. Each of the proteins was tested at 0.1 and 2 g/L …
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Synthesis of biodegradable hydrogel microparticles for vaccine protein delivery
… (ethylene glycol) acrylate molecule attached to ovalbumin protein. When a dendritic cell degrades the particle, the ovalbumin protein will be degraded, as will the connections between the polymer network that holds the particle together [2]. The particles degraded to 56% of their original size in …
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Ambient particulate matter as a trigger for acute exacerbations of asthma
… and Results: BALB/c mice were sensitised to ovalbumin and repeatedly challenged with a low mass concentration (~3 mg/m3) of aerosolised ovalbumin for 4 weeks. Animals received a single dose of ambient particulate matter, collected in the geographical centre of Sydney (PM10 i.e. < 10 micron …
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Adjuvant Interactions with Lipid Membranes and Their Effect on Cellular Immune Responses
… made in our lab was selected to co-deliver ovalbumin and dexamethasone based on its ability to solubilize dexamethasone, extend its release, and enhance its membrane permeability and internalization. The combination of MF59a, ovalbumin, and dexamethasone inhibited several pro-inflammatory …
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Delivery of antigens to dendritic cells as a platform for a vector-free cancer therapy
… intracellular delivery could be achieved. Then ovalbumin (OVA) was delivered as a model protein to assess the system's capability to prime dendritic cells against a particular antigen. Dendritic cells activated post-delivery were then cultured with isolated primary T cells in-vitro to determine …
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Polymeric microneedle systems for enhanced transdermal drug delivery
… drug ibuprofen sodium and the large protein ovalbumin (OVA). A range of hydrogel forming materials for MN production was evaluated to identify the most suitable super swelling hydrogel MN array that are hard in the dry state but, upon insertion into skin, rapidly take up interstitial fluid. …
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Effect of fatty acids and programming on the immune system
… in a mouse model of allergic sensitisation (to ovalbumin). There was reduced immediate hypersensitivity to ovalbumin in mice fed a diet rich in salmon oil and increased immediate hypersensitivity in mice fed a diet rich in beef tallow, but there was no effect of diet on airway responsiveness to …
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Role of Nlc Cells in Murine Models of T Cell-Dependent Responses
… can upregulate B cell antigen presentation of ovalbumin to na?T cells expressing a transgene specific to the ovalbumin derived peptide, OVAp. This increase is contact dependent and can occur in the absence of IFN-gamma . Moreover, the NK cell enhancement of B cell presentation of intact …
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HPV 16 Strukturproteine als Vehikel zur Immunisierung
… drei verschiedene Vehikelpräparationen mit Ovalbumin als Reportergen hergestellt und getestet werden: (i) Pseudovirionen, bei denen die für das Antigen kodierende Reporter-DNA in HPV 16-VLPs verpackt ist, (ii) VLPs, an die das Reportergen von außen chemisch gebunden ist und (iii) ein Peptid …
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Dietary bioactives and cardiovascular health
… (blackberry-polyphenols) and Cardio-Protein (ovalbumin-derived peptides) randomised controlled trials (RCTs). Our findings indicate that the consumption of ovalbumin-derived peptides for 6-weeks does not have an effect on BP, blood lipids or glycaemic profile in adults [Cardio-Protein RCT]; …
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