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Showing 1 to 12 of 12 for “"outer segment"”.

  1. The Role of Peripherin in Photoreceptor Outer Segment Morphogenesis

    Salinas, Raquel Ybanez2015

    … a highly evolved sensory cilium called the outer segment. The outer segment is a specialized cellular compartment that contains all of the protein machinery involved in converting the initial light signal into an electrical signal that can be ultimately transmitted to the brain. Outer …

    duke Repository record

  2. Deciphering Underlying Mechanisms Of Photoreceptor Outer Segment Degradation; Involvement Of Intracellular Trafficking

    Egbejimi, AnuoluwapoThe University of Texas Medical Branch at Galveston2022

    … and degradation of shed photoreceptor outer segment (POS). It has been shown that with age and as a result of cellular stress this process can become impaired. Impairment in this unique phagocytic process can lead to degeneration of the RPE cells as well as the adjacent photoreceptor …

    utmb Repository record

  3. The Interaction Between Acridine Orange And The Frog Retinal Rod Outer Segment.

    Corliss, David Alexander

    uab Repository record

  4. Molecular Dissection of Multifunctional Proteins in Rod Outer Segments

    Gospe, III, Sidney Maloch2011

    … transduction in rods is confined to the unique outer segment organelle, a modified primary cilium consisting of a stack of hundreds of flattened disc membranes enveloped by a single plasma membrane. By concentrating important signaling molecules on disc membranes, the outer segment provides an …

    duke Repository record

  5. Glucose metabolism in the outer segments of photoreceptor cells : its involvement in the phototransduction process

    Hsu, Shu-ChanUniversity of British Columbia1993

    … and function of glucose metabolism in the outer segments of photoreceptor cells were investigated using biochemical and immunocytochemical approaches. The presence of glycolytic enzymes in photoreceptor outer segments was detected by enzyme activity assays, Western blotting, and …

    ubc Repository record

  6. Synaptojanin1 is involved in endolysosomal trafficking in cone photoreceptors

    George, Ashley Amelia2015

    … demands. At one end of the photoreceptor is the outer segment; the site of photon detection and phototransduction. The outer segment requires a constant supply of new proteins and membranes to maintain proper function. At the opposite end of the cell is the site of synaptic transmission. The …

    washington Repository record

  7. The effects of circadian rhythms on visual thresholds

    O'Keefe, Timothy J.Virginia Polytechnic Institute and State University1984

    … for males is thought to occur because of rod outer segment shedding which also has a circadian rhythm. A circadian rhythm questionnaire was administered to the subjects and it was found that morningness and vigorousness related to visual thresholds.

    vt Repository record

  8. Effect of Melatonin and Dopamine in Site Specific Phosphorylation of Phosducin in Intact Retina

    Nkemdirim, Arinzechukwu Okere2005

    … dimer from the site of phototransduction in the outer segment of the photoreceptor cell to the inner segment, thereby decreasing light sensitivity and contributing to the process of light adaptation. Dopamine and melatonin are neuromodulators whose concentrations in the retina vary reciprocally …

    byu Repository record

  9. Regulation of rod photoreceptor phosphodiesterase (PDE6) by the glutamic acid -rich protein 2 (GARP2)

    Pentia, Dana C

    … associates with the disk membranes of the rod outer segment (ROS) of the photoreceptor cell. This association insures the high efficiency of activation by the G-protein, transducin, and the precise control of its inactivation. In addition to binding to transducin during visual excitation, PDE6 …

    unh-thes Repository record

  10. Bioactive Peptides as Antibacterial Agents and Visual Transduction

    Carty, Symone LouiseUniversity of Houston2024

    … formation of the rod and cone photoreceptor outer segments of the retina, which are the organelles responsible for visual transduction. Defective or absent PRPH2 protein results in various blinding retina diseases such as macular degeneration and retinitis pigmentosa (RP), which range in …

    houston Repository record

  11. Understanding the genetics and function of complex human retinal phenotypes

    Currant, HannahUniversity of Cambridge2020

    … I next performed GWAS of the thickness of the outer retinal layers, including both the component photoreceptor cell layers (the outer nuclear layer, inner segment, and outer segment), and the retinal pigment epithelium layer. I explored how genetic variation was affecting the outer retinal …

    cambridge Repository record

  12. RATE-LIMITING STEP OF CONE PHOTOTRANSDUCTION RECOVERY AND OGUCHI DISEASE MECHANISMS

    Chen, Frank2016

    … is required for GRK1 membrane association and outer segment targeting. Altogether our data add significantly to understanding the structure and function of GRK1, which is one of the least understood molecules involved in vertebrate phototransduction.</p>

    vcu Repository record