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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 295 for “"outer membrane"”.
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Protein Composition of the Outer Membrane of Rhodopseudomonas Sphaeroides: Isolation of the Major Outer Membrane Protein
The outer membrane protein profile of Rhodopseudomonas sphaeroides was characterized on SDS-polyacrylamide gels. Solubilization of the outer membrane at 75(DEGREES)C as opposed to room temperature solubilization resulted in the dissociation of 75, 72, and 68 kilodalton polypeptide aggregates into …
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ACCELERATING WHOLE-CELL BIOCATALYSIS BY ENHANCING OUTER MEMBRANE PERMEABILITY
… research addresses this critical issue by using membrane engineering approaches. Two E. coli strains with genetically altered outer membrane structures were used in the study, a lipopolysaccarides (LPS) mutant SM101 and a Braun's lipoprotein mutant E609L. The effects of outer membrane mutation on …
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Bacterial Outer Membrane Vesicles. Mediators of virulence and antibiotic resistance.
Outer membrane vesicles (OMV) have the size of nanoparticles and are released from the outer membrane of most Gram-negative bacteria. The OMV reflect the composition of the bacterial outer membrane, including lipids and virulence factors specific for the pathogen, and are involved in pathogenesis …
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The role of Moraxella catarrhalis outer membrane proteins in pathogenesis
… component 3 (C3) for which M. catarrhalis outer membrane proteins “ubiquitous surface proteins” (Usp) A1/A2 are responsible. No other pathogenic bacterium is known to bind ACT. The ACT is a serine protease inhibitor playing important part in antiprotease lung protection and …
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An analysis of the outer membrane of desulfovibrio vulgaris (Woolwich)
… by the selective solubilisation of cell membranes by sarkosyl. Three Omps (Omps 1, 2 & 3) occur consistently in the OMs of C-Fe, NC & C+Fe cells. NC C+Fe OMs have, in addition, minor proteins absent from C-Fe OMs. Omp2 band is seen to be enhanced in C-Fe and NC OMs as indicated by PAGE. …
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The Translocase of the Outer Membrane of Mitochondria (TOM complex)
… a multisubunit assembly in the mitochondrial outer membrane, mediates targeting and membrane translocation of virtually all nuclear-encoded mitochondrial preproteins analyzed so far. In the present study the mechanisms by which the TOM complex recognizes different precursor proteins and …
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Development of Computational Antibiotic Screening Platform Across Bacterial Outer Membrane Proteins
… of small molecule drugs across bacterial outer membrane proteins, with a goal of accelerating the antibiotic discovery process. We applied all-atom and coarse-grained molecular modeling, enhanced sampling techniques, and a parallel computing environment to maximize the performance. We …
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Characterization of an outer membrane protein: macromolecular complex of Neisseria gonorrhoeae
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Characterisation of the virulence-related, outer-membrane proteins of B. pertussis
At the beginning of this study, knowledge of autotransporter proteins was in its infancy and the B. pertussis proteins pertactin, BrkA and tracheal colonisation factor (Tcf) had not been recognised as members of this family. However, the sequence similarity between these Bordetella proteins and a …
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Investigating the mechanism of LolB, the Bacterial Outer Membrane Lipoprotein Receptor
In Gram-negative bacteria, the outer membrane constitutes the first line of defence against toxic compounds including antibiotics. Lipoproteins are vital structural elements of this barrier and crucial components of machineries underpinning its generation and maintenance. Proper localisation of …
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Analysis and optimization of immune responses elicited by Outer Membrane Vesicles (OMVs)
Outer membrane vesicles (OMVs) are spheroidal particles released from all gram-negative bacteria and exert different biological functions. OMVs carry many microbe-associated molecular patterns (MAMPs) such as peptidoglycan, lipopolysaccharide (LPS), and lipoproteins and can be decorated with …
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Bacterial outer membrane vesicles (OMVs) as a platform for personalized cancer vaccines
… preclinical models and human patients. Bacterial Outer Membrane Vesicles (OMVs) are naturally produced by all Gram-negative bacteria. They contain several Microbe-Associated-Molecular Patterns (MAMPs), crucial for stimulating innate immunity and promoting adaptive immune responses. The ability to …
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NEW INSIGHTS INTO THE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION DURING APOPTOSIS
… proceeds in a linear fashion. Mitochondria outer membrane permeabilization (MOMP) and the release of intermembrane space proteins (e.g., cytochrome c) are early events during mitochondria-mediated apoptotic signaling. In addition, Apaf-1 is a critical component of the mitochondrial pathway …
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Studies on the outer membrane of Pseudomonas aeruginosa and associated resistance properties
… in the fatty acids of the cytoplasmic membrane, increase in expression of OprG, decrease in susceptibility to EDTA as an outer membrane permeabilising agent and an increase in negativity of the cell surface charge were observed as cells became more resistant to BKC. In strain OO14 a …
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Outer Membrane Proteins Associated With Utilization of Chondroitin Sulfate by Bacteroides Thetaiotaomicron
… location. Presumably some components of the outer membrane (OM) facilitates entry of CS into the cell, but these have not been identified. The approach used to obtain an initial characterization of this OM system was to isolate the OM of B. thetaiotaomicron and then to identify proteins which …
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Plasmid Structure and Function in Plant-Pathogenic Pseudomonas Syringae (outer-Membrane Proteins)
Thirty isolates of Pseudomonas syringae pv/ tabaci, pv. angulata, (pathogens on tobacco) pv. coronafaciens, and pv. striafaciens (pathogens on oat) were examined for plasmid DNAs. The strains were obtained from plants throughout the world and some over 30 years ago. Sixteen of the twenty-two …
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Interaction of the I Colicins With the Outer Membrane of Escherichia Coli: I. Purification and Characterization of the Colicin I Receptor. Ii. Proteolytic Activity Associated With the Outer Membrane
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1982.
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Outer Membrane Porin Regulation among Different Sequence Types of Escherichia coli Clinical Isolates
… E. coli can decrease the permeability of its outer membrane through porin downregulation, contributing to β-lactam resistance. Aberrations in permeability correlate with decreased carbapenem susceptibility when the organism produces an extended-spectrum β-lactamase or plasmid-encoded AmpC. …
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Investigation of the role of TamAB in Salmonella pathogenesis and outer membrane homeostasis
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
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Exploring the Polyclonal Antibody Responses Induced by Klebsiella pneumoniae Derived Outer-Membrane Vesicles
… are used by K. pneumoniae including a thick outer capsule, lipopolysaccharide (LPS), siderophores, and key metabolism and adhesion genes. These virulence factors assist in resisting a wide range of immunological and environmental stressors (complement, phagocytosis, antimicrobials, etc.). …
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