Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 96 for “"osteogenesis"”.
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Effects of nicotine on osteogenesis
… effects of systemically administered nicotine on osteogenesis and angiogenesis. The orthopedic expansion of a suture is a non-invasive method directly related to orthodontic treatment. This study examined the actions of nicotine related to the vascularly related osteogenic response elicited by …
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Understanding Hearing Loss in Osteogenesis Imperfecta
… is a common yet understudied manifestation of osteogenesis imperfecta (OI), a hereditary disease of the connective tissues caused by mutations in collagen type I. The hallmark of OI is bone fragility, leading to frequent fractures in childhood that tend to decrease after puberty. Hearing loss …
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Electrical stimulation and osteogenesis / by Sir Dennis Patterson
Typescript (photocopy)
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The Effect of Mandibular Distraction Osteogenesis On Condylar Rotation in Rabbits
<p>Distraction osteogenesis (DO) is the gradual lengthening of a healing bone. This surgical technique can be applied to the jawbone to correct an asymmetry or deficiency of the mandible. DO has been added to the list of treatment options for patients with craniofacial anomalies or excessive dental …
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Surgical restoration of maxillofacial defects by transport disc distraction osteogenesis : engineering aspects
Transport disc distraction osteogenesis (TDDO) harnesses the natural healing mechanisms of bone to regenerate, and thus repairs, bone defects. Presently, no system is available for applying TDDO to the maxillary anatomy; specifically anterior-to-posterior distraction on a three-dimensional …
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Procollagen Biosynthesis and Osteoblast Malfunction in the G610C Mouse Model of Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is a hereditary disease that disrupts bone formation and function resulting in skeletal deformities and fragile bones. OI is diagnosed based on clinical and radiological examination, with patient symptoms ranging in severity from relatively mild (increased incidence of …
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Skeletal muscle weakness and mitochondrial dysfunction in the osteogenesis imperfecta murine (oim) model
Osteogenesis imperfecta (OI), also commonly referred to as brittle bone disease, is a heritable connective tissue disorder occurring in roughly 1:15,000 births. OI arises as a result of mutations in the type I collagen genes, COL1A1 and COL1A2, approximately 85 % of the time with the remaining 15 % …
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Comparative osteogenesis of equine mesenchymal stem cells isolated from bone marrow, adipose tissue, and synovium
The experiments in this study were carried out to define the osteogenic potential of equine MSCs derived from synovium, bone marrow, and adipose tissue maintained under the same culture conditions. Equine MSCs were isolated from synovium [SYN], bone marrow [BM] and adipose tissue [AD], expanded in …
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Assessment of Dental Anomalies and Potential Application of Optical Coherence Tomography in Pediatric Patients with Osteogenesis Imperfecta
L'abstract è presente nell'allegato / the abstract is in the attachment
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Calibration and Validation of an in Vitro Ultrasound Device to Deliver Targeted Thermal Enhancement of hMSC Osteogenesis
… of thermal dosing on hMSC cultures induced to osteogenesis was explored, and it was determined that thermal dosing via heat shocking in an incubator for one hour upregulates alkaline phosphatase (ALP) activity and calcium deposition, indicators of bone formation. In this project, the thermal …
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Functional anatomy, osteogenesis and bone microstructure of the appendicular system of African mole-rats (Rodentia: Ctenohystrica: Bathyergidae)
In comparison to their ecophysiological and behavioral aspects, the skeletal system of African mole-rats (Bathyergidae) has been relatively understudied. Only a few studies have assessed their skeletal system, but these have mostly focused on their cranial and dental systems, with little attention …
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Osteogenesis During Early Healing Around Titanium and Titanium Zirconium Implants: Immunohistochemistry and mRNA Expression of Bone Markers in Miniature Pigs
<p><strong>Background: </strong>To better understand the effect of implant surface modification on bone, more information is needed on the early stages of bone healing around dental implants in vivo. Quantitative reverse transcription polymerase chain reaction (QRT-PCR) is a method that can be …
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Adipose-Derived Stem Cell Osteogenic Differentiation: A Study of the Influence of Extracellular Matrix on the Differentiation Process
… (BTE), ADSC are commonly used for in vitro osteogenesis studies. Although these cells display similar characteristics as bone marrow-derived stem cells (BMSC), the mechanisms and pathways that these cells utilize to differentiate down the osteogenic pathway are still unclear. Specific …
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Evaluation of the clinical outcome of curvilinear transport distraction osteogenesis and revascularised fibula free flaps in the reconstruction of large post-maxillectomy defects
Background: Maxillary defects caused by trauma or tumour resection in the head and neck region can be devastating to the patient from a cosmetic and functional perspective. Patients who undergo maxillectomy procedures experience a substantial deterioration in their primary oral functions such as …
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Elucidating Cause-Effect Relationships between Extracellular Matrix Signaling and Mesenchymal Stem Cell Differentiation
… morphogenesis or bone fracture healing on MSC osteogenesis was investigated. Second, collagen-mimetic proteins (Scl2) were modified in order to incorporate them in a 3D network, and cell adhesion and activation of cell signaling were evaluated, as well. Finally, the influence of integrin ?1 and …
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Differential expression and phenotypic activities of osterix in equine mesenchymal stem cell populations
… Mesenchymal stem cell (MSC) precursors undergo osteogenesis to give rise to osteoblasts, which are responsible for bone matrix synthesis and mineralization. Osteogenesis is regulated by two master transcription factors, runt-related transcription factor 2 (RUNX2) and Osterix (OSX), with …
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Effect of Implant Surface Microtopography by Hydroxyapatite Grit-Blasting on Adhesion, Proliferation and Differentiation of Osteoblast-like Cell Line, MG-63
… is to evaluate the potential of the in vitro osteogenesis of microtopographically modified surfaces, RBM (resorbable blasting media) surfaces that generate a hydroxyapatite grit-blasting. Methods: First, to produce microtopographically modified surfaces, we made the RBM surfaces using a …
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The role of autophagy in protecting periodontium integrity, and lipopolysaccharide-induced osteoclast differentiation
… disease. While the stem cells concerned in both osteogenesis and osteoclastogenesis are different, they both originate from the bone marrow, therefore the same primary human bone marrow cells containing the specific stem cell populations required for osteogenesis or osteoclastogenesis were used …
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The Interplay Between Bone Homeostasis, Permeability, and Fracture Toughness
… understand bone fragility origins, we focus on osteogenesis imperfecta, a genetic disorder marked by defective collagen, abnormal mineralization, and increased porosity. Our findings indicate that osteogenesis imperfecta presents distinct features depending on biological sex, and that in healthy …
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