Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"osteochondral repair"”.
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MSC-LADEN SCAFFOLDS FOR OSTEOCHONDRAL REPAIR
I difetti osteocondrali compromettono l’unità funzionale formata dalla cartilagine articolare, dall’osso subcondrale e dalla loro interfaccia. Le strategie cliniche attuali non consentono di ripristinare in modo affidabile questa organizzazione complessa, evidenziando la necessità di scaffold in …
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Exogenous mesenchymal stromal cells in osteochondral repair
… human bone marrow derived MSCs into a mouse knee osteochondral injury model were investigated in young C57Bl/6 mice, aged C57Bl/6 mice and GNL3 heterozygote mice. MSC treatment was associated with improved osteochondral tissue repair in young C57Bl/6 mice but this was more limited in aged C57BL/6 …
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The role of the bone marrow niche and G-CSF in osteochondral repair
… pain and maintain joint function. Procedures for osteochondral repair, such as drilling or microfracture of the subchondral bone, are thought to restore cartilage by delivering bone marrow cells to the defect site. However, the specific identity or contribution of these cells to the repair process …
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The influence of ECM on mesenchymal stromal/stem cell activity and their interactions with monocytes/macrophages
… as marrow stimulation or microfracture, aims to repair this damage by promoting endogenous healing. However, the resulting repair tissue often lacks the properties of native cartilage, raising questions about the long-term effectiveness of this approach. Therefore, to enhance the outcome of this …
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Biodegradable Hydrogel Composites for Growth Factor and Stem Cell Delivery in Osteochondral Tissue Engineering
… has a limited endogenous ability for self-repair and current clinical treatments for damaged or diseased cartilage tissue are insufficient. Additionally, there is a biological and mechanical interplay between cartilage and the underlying subchondral bone, linking the …