Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"osteochondral defect"”.
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Biomaterials for tissue engineering for rheumatoid arthritis based on controlling dendritic cell phenotype
… progression was differentially observed in the osteochondral defect of the knee joint of RA-induced rabbit, depending on type of biomaterial scaffold implanted into the defect. Collectively, these results demonstrate the multifunctional impacts of inherently different biomaterials on in vitro …
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Minimally invasive CT-guiding excision of benign bone tumours
… fibrous histiocytoma, subacute osteitis and an osteochondral defect with geode cyst formation. Of the 2 patients where OO was not suspected preoperatively, chondroblastoma was confirmed in one while a benign spindle cell lesion was reported in the other. Overall histological yield was thus 100%. …
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Modulation of Chondrogenic and Osteogenic Differentiation of Mesenchymal Stem Cells through Signals in the Extracellular Microenvironment
Damage to synovial joints results in osteochondral defects that only heal with inferior fibrous repair tissue. Since mesenchymal stem cells (MSCs) play a vital role in the natural development, maintenance, and repair of cartilage and bone, tissue engineering strategies to enhance functional …
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Biodegradable Hydrogel Composites for Growth Factor and Stem Cell Delivery in Osteochondral Tissue Engineering
… delivery vehicles to study the regeneration of osteochondral tissue. First, we investigated the release of growth factors from acellular hydrogel composites containing gelatin microparticles (GMPs) to stimulate the repair of cartilage tissue in an in vivo osteochondral defect model. Transforming …
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Management of cartilage deficiency by applying extracellular matrix membrane on bone marrow stimulation technique and evaluating the quality of repaired cartilage
… in repair of large full-thickness cartilage defects was investigated in this study. Rabbits were divided into four groups: the defect remained untreated as a negative control; performance of BMS only (BMS group); BMS followed by supplementation of autologous bone marrow buffy coat (Buffy coat …
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Comparison of Cone-Beam Computed Tomography (CBCT), Fan-Beam Computed Tomography (FBCT), and Low-Field Magnetic Resonance Imaging (MRI) for Detection of Equine Fetlock Lesions
… (P1) sagittal groove fissure, P1 dorsoproximal osteochondral defect, palmar/plantar osteochondral disease (POD), and heterotopic mineralisation in 35 equine cadaver limbs between CBCT, FBCT, and MRI using pathological findings as a gold standard (Chapter 3, 5, 6, and 7). The second part of the …
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Pain alleviating effects of mesenchymal stem/stromal cells and derived extracellular vesicles in osteoarthritis
… as an animal model for OA pain research. An osteochondral defect (OD), a common clinical observation in joints leading to OA, was created in sheep, and the sensory neurone properties of these operated sheep were investigated. Increased sensory neurone excitability and increased transient …
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Klinische und kernspintomographische Ergebnisse nach Implantation von artifiziellen TruFit-Zylindern in die Entnahmedefekte bei der autologen Knorpel-Knochen-Transplantation
Ziel der Arbeit: In der Literatur wird die Entnahmemorbidität nach Knorpel-Knochen-Transplantation (OCT) mit bis zu 50% angegeben (Valderrabano et al. 2009). In der vorliegenden Studie wurde geprüft, ob die Implantation von TruFit-Zylindern der Firma Smith & Nephew in die Entnahmedefekte einen …