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Showing 1 to 20 of 61 for “"ossification"”.
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Analysis of the biochemical mechanisms of heterotopic ossification following musculoskeletal trauma
INTRODUCTION: Heterotopic ossification is the formation of bone in the soft tissues of the body. It is an increasingly prevalent complication following certain fractures and major orthopedic surgeries. It leads to many complications, including swelling, redness, pain, and disability due to limited …
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Correlation of the Epiphyseal Closure and Ossification of the Ulnar Sesamoid Bone of the Metacarpophalangeal Joint of the Thumb
… of the epiphyses of the hand and the time of ossification of the ulnar sesamoid of the metacarpophalangeal joint of the thumb.</p> <p>The time for these events was studied in twenty-three males and fourteen females for which appropriate hand radiographs were available. Radiographs were made …
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Bone growth following demineralized bone matrix implantation requires angiogenesis
Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear. In this study, we utilize an in vivo model of endochondral ossification in mice by implanting …
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THE EVOLUTIONARY DEVELOPMENT OF CROWN GALLOANSERAE SKULLS: TRACKING CHANGES IN GALLIFORM AND ANSERIFORM CRANIAL DEVELOPMENT
… species of Galloanserae from initial skull ossification to the adult stage. I began by constructing robust morphology-based staging criteria for nearhatching embryos of two species of anseriforms, mallard duck (Anas platyrhynchos) and swan goose (Anser cygnoides), because skull ossification …
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Chondrodystrophia foetalis in the foetus and the infant
… aid of X-rays. 4. The disease is present before ossification commences in any given bone and results in defective preparation for ossification in cartilage, causing a deficient attraction of true bone-forming cells. 5. It is highly probable that softness i of the skeleton due to disease affecting …
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A STUDY OF THE GROSS, MICROSCOPIC, ULTRASTRUCTURAL, AND COMPARATIVE ANATOMY AND DEVELOPMENT OF THE ARTICULAR SURFACES OF THE HUMAN SACROILIAC JOINT
… the primary hyaline cartilage anlage. Enchondral ossification progresses from the primary centre of ossification toward the articular surface. At maturity, a hyaline cartilage cap is left as the articular cartilage. On the iliac side, ossification of the cartilage anlage precedes cavitation of the …
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Expression and Function(s) of Parathyroid Hormone- Related Peptide in Intramembranous Bone Formation by Neonatal Rat Calvarial Cells In Vitro
… Whether or not PTHrP influences intramembranous ossification is less clear. The puipose of this study was to examine the expression of PTHrP and its receptor (PTH1R) by osteogenic cells involved in intramembranous ossification in vitro, and to determine the effect of exogenous PTHrP on this …
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Characterization of a Novel Nuclear Variant of Bmp2 and Coordinate Regulation of Col11a2 and Col27a1 by the Transcription Factor Lc-Maf
… replaced by bone. This process of endochondral ossification requires precisely coordinated expression of extracellular matrix proteins such as the cartilage-specific collagens. In this study, enhancer/reporter assays demonstrated that the transcription factor Lc-Maf inhibits the transcriptional …
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Sequência de ossificação craniana de Aparasphenodon brunoi Miranda-Ribeiro, 1920, com comentários sobre o condrocrânio e o desenvolvimento da ornamentação óssea (Amphibia, Anura, Hylidae)
… developmental stages, the sequence of cranial ossification, the cartilages and bones of the adult cranium, and the development of crests and spines that ornaments the cranial roof elements were described. Among the main resulta were the develoi;:ment of the prenaaal bone from two independent …
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Using diffuse idiopathic skeletal hyperostosis to determine age at death
… is a condition characterized spinally by ossification of the anterior longitudinal ligament resulting in fusion of vertebrae; and extraspinally by enthesopathies, ossification at sites of ligament or muscle attachments. Using the Terry Collection, housed at the Smithsonian Institution, …
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Ontogeny and evolutionary morphology of the skeleton in frogs
… history. Two methods are used. First, skull bone ossification sequences are examined within a phylogenetic context. Second, studies are made of ontogenetic shape change in the skull using thin-plate spline morphometrics. Important differences between pipoid skull development and that of other …
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Metal-doped silicate microparticles for collagen scaffold-guided endochondral bone regeneration
Endochondral ossification (EO) describes a process in which bone tissue builds up via a cartilaginous phase. In contrast to classical biomaterial approaches, which address bone regeneration via direct, intramembranous ossification (IO), a collagen scaffold was shown to stimulate endochondral …
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Potentiating effects of caffeine on the teratogenicity of acetazolamide in two strains of mice
… caudal vertebral centra revealed a reduction in ossification among C57BL/6J litters exposed to high dose acetazolamide or acetazolamide plus caffeine. These same centers of ossification were mildly affected by treatment in the SWV strain. In both strains the first cervical vertebrae (Cl) appeared …
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The roles of Rb, p107, and E2f4 in bone formation and embryonic development
… We find that Rb-inactivation impairs the ossification of several bones. These bone defects correlate with an inability of Rb-deficient osteoblasts to properly exit the cell cycle. Similarly, we find that the mutation of E2f4 causes defects in embryonic ossification that are accompanied by …
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A qualitative and quantitative investigation of structural morphology in the neonatal ilium
… developmental ilium may be attributable to early ossification patterning, non-weight bearing anatomical interactions or even to a predetermined genetic blueprint. It must also be postulated that whilst the observed patterning may be indicative of a predetermined inherent template, early non-load …
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Dysphagia and recurrent laryngeal nerve injury in anterior cervical discectomy and fusion
… disease, myelopathy, cervical canal stenosis or ossification of the posterior longitudinal ligament were identified according to prior inclusion and exclusion criteria. Statistical analysis was performed using odds ratio (OR) as the effective size. I2 was used to explore heterogeneity. For the …
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Effects of Binge Alcohol Exposure on Canonical Wnt Signaling During Fracture Repair
… chondrocyte hypertrophy and endochondral ossification. Western blot demonstrated that the temporal expression of stabilized beta-catenin in callus tissue was significantly disrupted by alcohol at days 1, 3, 6, 9, and 14 post fracture compared to controls. The disruption in beta-catenin …
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A qualitative and quantitative analysis of the developing human lumbar vertebral column
… displayed a structure predominantly driven by ossification with trabeculae in close proximity to the primary centre of ossification thicker and more mature than in peripheral regions, which displayed a radial pattern of thin trabeculae extending outwards from the ossification centre. The …
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The influence of osteochondrosis (OC), in yearling Standardbred horses on subsequent two and three-year old racing performance and the influence of sire on rates of OC in Illinois Standardbred horses
… that involves the failure of endochondral ossification affecting the articular cartilage. This generally occurs in the early orthopedic development in juvenile horses. Due to this, owners and trainers take great interest in early orthopedic developmental abnormalities as a predictor of …
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