Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"orthogonal ribosome"”.
-
Quantitative analysis of translational coupling in Escherichia coli
… where the upstream gene is translated by orthogonal ribosomes and the downstream gene by native ribosomes. This design allows us to precisely tune the translation of the upstream gene and then record its affect on the translation of the downstream gene. Using this general system, we show …
-
A General Platform for Ribosome Engineering
… approach. However, the properties of the natural ribosome limit existing work to close analogues of the canonical amino acids. This thesis develops a directed evolution technology to engineer ribosomes in vitro. The focus of this work is to create a general platform capable of identifying ribosome …