Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"orthogonal IL2"”.
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Precision Cytokine Therapy: Engineering and Delivery of CD8- and CAR-Tropic Interleukin-2 Variants
… expressing modified versions of interleukin 2 (IL2), a key T cell growth factor, using an adeno-associated viral (AAV) gene delivery system. Previous work by Yshii et al. (2022) demonstrated that AAV-mediated expression of wild type IL2 in the brain expanded immunosuppressive CD4+ regulatory T …